BIOMAT Database Logo BIOMAT Database Logo

CD2 induced apoptosis of peripheral T cells. 1997

M Rouleau, and B Mollereau, and A Bernard, and D Metivier, and M A Rosenthal-Allieri, and B Charpentier, and A Senik
Cellular Immunology and Transplantation Laboratory, Scientific Cancer Research Institute, Villejuif, France.

UI MeSH Term Description Entries
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013601 T-Lymphocytes Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen. T Cell,T Lymphocyte,T-Cells,Thymus-Dependent Lymphocytes,Cell, T,Cells, T,Lymphocyte, T,Lymphocyte, Thymus-Dependent,Lymphocytes, T,Lymphocytes, Thymus-Dependent,T Cells,T Lymphocytes,T-Cell,T-Lymphocyte,Thymus Dependent Lymphocytes,Thymus-Dependent Lymphocyte
D017209 Apoptosis A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth. Apoptosis, Extrinsic Pathway,Apoptosis, Intrinsic Pathway,Caspase-Dependent Apoptosis,Classic Apoptosis,Classical Apoptosis,Programmed Cell Death,Programmed Cell Death, Type I,Apoptoses, Extrinsic Pathway,Apoptoses, Intrinsic Pathway,Apoptosis, Caspase-Dependent,Apoptosis, Classic,Apoptosis, Classical,Caspase Dependent Apoptosis,Cell Death, Programmed,Classic Apoptoses,Extrinsic Pathway Apoptoses,Extrinsic Pathway Apoptosis,Intrinsic Pathway Apoptoses,Intrinsic Pathway Apoptosis
D018801 CD2 Antigens Glycoprotein members of the immunoglobulin superfamily which participate in T-cell adhesion and activation. They are expressed on most peripheral T-lymphocytes, natural killer cells, and thymocytes, and function as co-receptors or accessory molecules in the T-cell receptor complex. Antigens, CD2,T11 Erythrocyte-Binding Glycoprotein,CD2 Antigen,Antigen, CD2,Erythrocyte-Binding Glycoprotein, T11,T11 Erythrocyte Binding Glycoprotein

Related Publications

M Rouleau, and B Mollereau, and A Bernard, and D Metivier, and M A Rosenthal-Allieri, and B Charpentier, and A Senik
Effects of anti-CD2 monoclonal antibody: CD2- and CD95-mediated apoptosis of human peripheral T cells.
January 1999, Transplantation proceedings,
M Rouleau, and B Mollereau, and A Bernard, and D Metivier, and M A Rosenthal-Allieri, and B Charpentier, and A Senik
CD2-induced apoptosis in activated human peripheral T cells: a Fas-independent pathway that requires early protein tyrosine phosphorylation.
May 1996, Journal of immunology (Baltimore, Md. : 1950),
M Rouleau, and B Mollereau, and A Bernard, and D Metivier, and M A Rosenthal-Allieri, and B Charpentier, and A Senik
Ligation of either CD2 or CD28 rescues CD4+ T cells from HIV-gp120-induced apoptosis.
October 1995, European journal of immunology,
M Rouleau, and B Mollereau, and A Bernard, and D Metivier, and M A Rosenthal-Allieri, and B Charpentier, and A Senik
Ethanol-induced CD3 and CD2 hyporesponsiveness of peripheral blood T lymphocytes.
January 1992, Immunopharmacology and immunotoxicology,
M Rouleau, and B Mollereau, and A Bernard, and D Metivier, and M A Rosenthal-Allieri, and B Charpentier, and A Senik
Human peripheral CD2-/lo T cells: an extrathymic population of early differentiated, developing T cells.
September 2005, International immunology,
M Rouleau, and B Mollereau, and A Bernard, and D Metivier, and M A Rosenthal-Allieri, and B Charpentier, and A Senik
Apoptosis of activated CD8+/CD57+ T cells is induced by some combinations of anti-CD2 mAb.
October 1993, Journal of immunology (Baltimore, Md. : 1950),
M Rouleau, and B Mollereau, and A Bernard, and D Metivier, and M A Rosenthal-Allieri, and B Charpentier, and A Senik
Apoptosis of activated peripheral T cells.
January 1999, Transplantation proceedings,
M Rouleau, and B Mollereau, and A Bernard, and D Metivier, and M A Rosenthal-Allieri, and B Charpentier, and A Senik
Lamina propria T cells in Crohn's disease and other gastrointestinal inflammation show defective CD2 pathway-induced apoptosis.
March 1999, Gastroenterology,
M Rouleau, and B Mollereau, and A Bernard, and D Metivier, and M A Rosenthal-Allieri, and B Charpentier, and A Senik
Fas-independent apoptosis in T-cell tumours induced by the CD2-myc transgene.
January 2000, Cell death and differentiation,
M Rouleau, and B Mollereau, and A Bernard, and D Metivier, and M A Rosenthal-Allieri, and B Charpentier, and A Senik
Differentiation of regulatory T cells 1 is induced by CD2 costimulation.
September 2001, Journal of immunology (Baltimore, Md. : 1950),
Copied contents to your clipboard!