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The aim of this study was evaluation of interleukin-6 (IL-6) and interleukin-8 (IL-8) in creation of inflammation of lower airways in patients with chronic bronchitis. 32 patients with chronic bronchitis and 14 subjects of control group took part in this study. Spirometry (Jaeger eq.), bronchofibroscopy and bronchoalveolar lavage (Olympus eq.) were performed in every patient. Cytology and concentration of IL-6 and IL-8 (kits from R&D) were measured in 1 ml of lavage fluid recovered. The increased levels of IL-6 and IL-8 in BAL were correlated with clinical parameters. We conclude that these two cytokines participate in creation of inflammatory changes of lower respiratory tract in chronic bronchitis.
K Jahnz-Rózyk, and
T Płusa, and
M Faber, and
L Stepnowski, and
E Pirozyńska, and
Z Pojda
September 1996,
International archives of allergy and immunology,
K Jahnz-Rózyk, and
T Płusa, and
M Faber, and
L Stepnowski, and
E Pirozyńska, and
Z Pojda
November 2001,
Chinese medical journal,
K Jahnz-Rózyk, and
T Płusa, and
M Faber, and
L Stepnowski, and
E Pirozyńska, and
Z Pojda
May 1997,
Respiratory medicine,
K Jahnz-Rózyk, and
T Płusa, and
M Faber, and
L Stepnowski, and
E Pirozyńska, and
Z Pojda
December 1988,
Klinicheskaia meditsina,
K Jahnz-Rózyk, and
T Płusa, and
M Faber, and
L Stepnowski, and
E Pirozyńska, and
Z Pojda
December 2002,
Journal of the American Geriatrics Society,
K Jahnz-Rózyk, and
T Płusa, and
M Faber, and
L Stepnowski, and
E Pirozyńska, and
Z Pojda
February 1990,
Pneumologie (Stuttgart, Germany),
K Jahnz-Rózyk, and
T Płusa, and
M Faber, and
L Stepnowski, and
E Pirozyńska, and
Z Pojda
October 1999,
The Journal of laboratory and clinical medicine,
K Jahnz-Rózyk, and
T Płusa, and
M Faber, and
L Stepnowski, and
E Pirozyńska, and
Z Pojda
January 1998,
The European respiratory journal,
K Jahnz-Rózyk, and
T Płusa, and
M Faber, and
L Stepnowski, and
E Pirozyńska, and
Z Pojda
August 1997,
The journal of medical investigation : JMI,
K Jahnz-Rózyk, and
T Płusa, and
M Faber, and
L Stepnowski, and
E Pirozyńska, and
Z Pojda
February 1990,
Biulleten' eksperimental'noi biologii i meditsiny,
