[Disturbances of wakefulness, sleep and respiratory function in Steinert's disease]. 1977

F Leygonie-Goldenberg, and M Perrier, and P Duizabo, and A Bouchareine, and A Harf, and J Barbizet, and J D Degos

36 night sleep recordings were carried out on 15 patients suffering from myotonia dystrophica. 9 of these patients complained of diurnal hypersomnia. 10 patients had a disturbance of night sleep with a reduction of REM sleep sometimes associated with interruption of the recording with an increase in the light stages of sleep or alternatively with an increase of REM sleep with a reduction in the latency period of the first paradoxical sleep or with narcoleptic elements. 13 patients had abnormally early abolition of chin EMG activity, almost on falling asleep. 11 cases had pathological apnoeic episodes during sleep and in 9 of the 10 patients who underwent respiratory function studies there was a restrictive airways defect. In addition 9 had frank hypoxia without hypercapnia and 4 a right to left shunt. 3 clinically unaffected patients but with affected relatives were also investigated, 2 were found to have sleep disturbances 1 of which was associated with early abolition of tone.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D009223 Myotonic Dystrophy Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2. Dystrophia Myotonica,Myotonic Dystrophy, Congenital,Myotonic Myopathy, Proximal,Steinert Disease,Congenital Myotonic Dystrophy,Dystrophia Myotonica 1,Dystrophia Myotonica 2,Myotonia Atrophica,Myotonia Dystrophica,Myotonic Dystrophy 1,Myotonic Dystrophy 2,PROMM (Proximal Myotonic Myopathy),Proximal Myotonic Myopathy,Ricker Syndrome,Steinert Myotonic Dystrophy,Steinert's Disease,Atrophica, Myotonia,Atrophicas, Myotonia,Congenital Myotonic Dystrophies,Disease, Steinert,Disease, Steinert's,Dystrophia Myotonica 2s,Dystrophia Myotonicas,Dystrophica, Myotonia,Dystrophicas, Myotonia,Dystrophies, Congenital Myotonic,Dystrophies, Myotonic,Dystrophy, Congenital Myotonic,Dystrophy, Myotonic,Dystrophy, Steinert Myotonic,Myopathies, Proximal Myotonic,Myopathy, Proximal Myotonic,Myotonia Atrophicas,Myotonia Dystrophicas,Myotonic Dystrophies,Myotonic Dystrophies, Congenital,Myotonic Dystrophy, Steinert,Myotonic Myopathies, Proximal,Myotonica, Dystrophia,Myotonicas, Dystrophia,PROMMs (Proximal Myotonic Myopathy),Proximal Myotonic Myopathies,Steinerts Disease,Syndrome, Ricker
D012120 Respiration Disorders Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available. Disorder, Respiration,Disorders, Respiration,Respiration Disorder
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012893 Sleep Wake Disorders Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle. Sleep Disorders,Long Sleeper Syndrome,Short Sleep Phenotype,Short Sleeper Syndrome,Sleep-Related Neurogenic Tachypnea,Subwakefullness Syndrome,Disorder, Sleep,Disorder, Sleep Wake,Disorders, Sleep,Disorders, Sleep Wake,Long Sleeper Syndromes,Neurogenic Tachypnea, Sleep-Related,Neurogenic Tachypneas, Sleep-Related,Phenotype, Short Sleep,Phenotypes, Short Sleep,Short Sleep Phenotypes,Short Sleeper Syndromes,Sleep Disorder,Sleep Phenotypes, Short,Sleep Related Neurogenic Tachypnea,Sleep Wake Disorder,Sleep-Related Neurogenic Tachypneas,Sleeper Syndrome, Long,Sleeper Syndrome, Short,Sleeper Syndromes, Long,Sleeper Syndromes, Short,Subwakefullness Syndromes,Syndrome, Long Sleeper,Syndrome, Short Sleeper,Syndrome, Subwakefullness,Syndromes, Long Sleeper,Syndromes, Short Sleeper,Syndromes, Subwakefullness,Tachypnea, Sleep-Related Neurogenic,Tachypneas, Sleep-Related Neurogenic,Wake Disorder, Sleep,Wake Disorders, Sleep

Related Publications

F Leygonie-Goldenberg, and M Perrier, and P Duizabo, and A Bouchareine, and A Harf, and J Barbizet, and J D Degos
January 2006, Journal of neural transmission. Supplementum,
F Leygonie-Goldenberg, and M Perrier, and P Duizabo, and A Bouchareine, and A Harf, and J Barbizet, and J D Degos
January 1993, Journal of psychosomatic research,
F Leygonie-Goldenberg, and M Perrier, and P Duizabo, and A Bouchareine, and A Harf, and J Barbizet, and J D Degos
March 2006, Swiss medical weekly,
F Leygonie-Goldenberg, and M Perrier, and P Duizabo, and A Bouchareine, and A Harf, and J Barbizet, and J D Degos
July 1992, The European respiratory journal,
F Leygonie-Goldenberg, and M Perrier, and P Duizabo, and A Bouchareine, and A Harf, and J Barbizet, and J D Degos
January 2011, Handbook of clinical neurology,
F Leygonie-Goldenberg, and M Perrier, and P Duizabo, and A Bouchareine, and A Harf, and J Barbizet, and J D Degos
January 1998, Zhurnal evoliutsionnoi biokhimii i fiziologii,
F Leygonie-Goldenberg, and M Perrier, and P Duizabo, and A Bouchareine, and A Harf, and J Barbizet, and J D Degos
January 2014, Neurology international,
F Leygonie-Goldenberg, and M Perrier, and P Duizabo, and A Bouchareine, and A Harf, and J Barbizet, and J D Degos
October 1995, Journal of applied physiology (Bethesda, Md. : 1985),
F Leygonie-Goldenberg, and M Perrier, and P Duizabo, and A Bouchareine, and A Harf, and J Barbizet, and J D Degos
October 1995, Journal of applied physiology (Bethesda, Md. : 1985),
F Leygonie-Goldenberg, and M Perrier, and P Duizabo, and A Bouchareine, and A Harf, and J Barbizet, and J D Degos
July 2013, International journal of cardiology,
Copied contents to your clipboard!