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A large number of developmentally regulated DNA rearrangements occur during the development of the macronucleus in Tetrahymena thermophila. Tlr1 is a deletion element which has large inverted repeats near the rearrangement junctions and deletes more than 13 kbp of internal DNA. Previous analysis of caryonidal lines revealed alternate left junctions for the Tlr1 rearrangement in B strain cells. We show here that C2 strain Tetrahymena also use alternate rearrangement junctions. We have mapped and sequenced two additional rearrangement variants and find that both the left and right junctions can vary over a range of approximately 200 bp. We also demonstrate the presence of sequence microheterogeneity in the most commonly found Tlr1 rearrangement product.
N S Patil, and
P M Hempen, and
R A Udani, and
K M Karrer
September 1988,
Molecular and cellular biology,
N S Patil, and
P M Hempen, and
R A Udani, and
K M Karrer
June 1988,
Nucleic acids research,
N S Patil, and
P M Hempen, and
R A Udani, and
K M Karrer
September 1989,
Nucleic acids research,
N S Patil, and
P M Hempen, and
R A Udani, and
K M Karrer
January 1987,
Molecular and cellular biology,
N S Patil, and
P M Hempen, and
R A Udani, and
K M Karrer
September 1994,
Molecular and cellular biology,
N S Patil, and
P M Hempen, and
R A Udani, and
K M Karrer
February 2004,
Gene,
N S Patil, and
P M Hempen, and
R A Udani, and
K M Karrer
January 1996,
Biology of the cell,
N S Patil, and
P M Hempen, and
R A Udani, and
K M Karrer
April 2002,
Eukaryotic cell,
N S Patil, and
P M Hempen, and
R A Udani, and
K M Karrer
February 2015,
Eukaryotic cell,
N S Patil, and
P M Hempen, and
R A Udani, and
K M Karrer
June 1996,
The EMBO journal,
