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The cartilage composed of chondrocytes and their surrounding extracellular matrix, and mechanical motion of joint may influence on the metabolism of cartilage. In order to determine whether non-weight bearing status alter the metabolism of cartilage, we made histological and biochemical analysis with incorporation of 35S and the distribution of the molecular size of proteoglycans produced in the case of disused cartilage. Histologically, there were seen no disorder in cell arrangement, but poorer in cellularity and thinner in cartilage width as compared with normal one. Biochemical analysis, however demonstrate that incorporation of 35S in newly synthesized glycosaminoglycan (GAG) was lower and the molecular size also smaller than that of control suggesting that mechanical stress is an important environmental factor in maintaining the differential function of the cartilage.
Y Yutani, and
K Inui, and
T Koike, and
Y Yamano
January 1987,
Bulletin of the Hospital for Joint Diseases Orthopaedic Institute,
Y Yutani, and
K Inui, and
T Koike, and
Y Yamano
August 2014,
The Journal of bone and joint surgery. American volume,
Y Yutani, and
K Inui, and
T Koike, and
Y Yamano
October 2019,
Cartilage,
Y Yutani, and
K Inui, and
T Koike, and
Y Yamano
October 1993,
The Biochemical journal,
Y Yutani, and
K Inui, and
T Koike, and
Y Yamano
November 1978,
Biochimica et biophysica acta,
Y Yutani, and
K Inui, and
T Koike, and
Y Yamano
September 1981,
Clinical orthopaedics and related research,
Y Yutani, and
K Inui, and
T Koike, and
Y Yamano
January 1993,
The Biochemical journal,
Y Yutani, and
K Inui, and
T Koike, and
Y Yamano
October 2000,
The Journal of experimental zoology,
Y Yutani, and
K Inui, and
T Koike, and
Y Yamano
December 1976,
The Journal of rheumatology,
Y Yutani, and
K Inui, and
T Koike, and
Y Yamano
May 1987,
The Journal of rheumatology,
