Portable/wearable artificial kidney (WAK) - initial evaluation. 1976

R L Stephens, and S C Jacobsen, and E Atkin-thor, and W Kolff

This report discusses the modus operandi and results achieved using this new mode of haemodialysis. An insulated 20 L dialysate bath acts as a carrying case for the system. When empty the case is large enough to hold the wearable module and complete supplies for one week's operation. The total weight is 17 kg. The wearable unit consists of a combined blood and dialysate pump (1.2 kg), rechargeable batteries, tubing, Dow dialyser and charcoal regeneration module with a total weight of 3.5kg. Ideally the patient dialyses using a single needle some 3 hours/day, 6 days/week. It is necessary for the wearable module to be connected to the 20 L dialysate bath for an average of 90 minutes to achieve adequate urea and 5+ removal. One patient was dialysed on 35 consecutive days and 4 others were dialysed intermittently. Routine laboratory tests and mass balance studies were performed on all patients. Ultrafiltration rates reached 700 ml/hour, routine serum chemistries remained stable and mass balance studies demonstrated a daily removal of urea 14-20 G, creatinine 1500-2000 mg, uric acid 500-900 mg and K+ 30-55 mEq. It is concluded that dialy dialysis with WAK is biochemically adequate and also permits the patient a much less restricted esistence.

UI MeSH Term Description Entries
D007688 Kidneys, Artificial Devices which can substitute for normally functioning KIDNEYS in removing components from the blood by DIALYSIS that are normally eliminated in the URINE. Artificial Kidney,Kidney, Artificial,Artificial Kidneys,Blood Dialyser,Blood Dialyzers,Hemodialyser,Hemodialyzers,Renal Dialysis Machine,Blood Dialysers,Blood Dialyzer,Dialyser, Blood,Dialysers, Blood,Dialysis Machine, Renal,Dialysis Machines, Renal,Dialyzer, Blood,Dialyzers, Blood,Hemodialysers,Hemodialyzer,Machine, Renal Dialysis,Machines, Renal Dialysis,Renal Dialysis Machines
D005069 Evaluation Studies as Topic Works about studies that determine the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. Critique,Evaluation Indexes,Evaluation Methodology,Evaluation Report,Evaluation Research,Methodology, Evaluation,Pre-Post Tests,Qualitative Evaluation,Quantitative Evaluation,Theoretical Effectiveness,Use-Effectiveness,Critiques,Effectiveness, Theoretical,Evaluation Methodologies,Evaluation Reports,Evaluation, Qualitative,Evaluation, Quantitative,Evaluations, Qualitative,Evaluations, Quantitative,Indexes, Evaluation,Methodologies, Evaluation,Pre Post Tests,Pre-Post Test,Qualitative Evaluations,Quantitative Evaluations,Report, Evaluation,Reports, Evaluation,Research, Evaluation,Test, Pre-Post,Tests, Pre-Post,Use Effectiveness
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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