Biomaterial Database

Temperature guardian neurons in the preoptic area of the hypothalamus. 1997

D Basta, and B Tzschentke, and M Nichelmann

Institut für Biologie, Humboldt-Universität zu Berlin, Germany. dietmar.basta@rz.hu-berlin.de

Applying the slice method extracellular recordings of 218 hypothalamic neurons in Muscovy ducks during sinusoidal temperature changes were investigated. Seven neurons reacted in a hitherto unknown manner to temperatures very near the physiological limits. Four were exclusively sensitive to temperatures around 36.1 degrees C and three to temperatures around 42.3 degrees C. We recommend to call this kind of neurons temperature guardian neurons. The presented results suggest that the current neuronal model of temperature regulation of vertebrates should be extended by aspects of the two-tier theory of Bligh [J. Bligh, The thermosensitivity of the hypothalamus and thermoregulation in mammals, Biol. Rev. 41 (1966) 317-367].

UI	MeSH Term	Description	Entries
D009474	Neurons	The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.	Nerve Cells,Cell, Nerve,Cells, Nerve,Nerve Cell,Neuron
D011301	Preoptic Area	Region of hypothalamus between the ANTERIOR COMMISSURE and OPTIC CHIASM.	Area Preoptica,Lateral Preoptic Area,Medial Preoptic Area,Preoptic Nuclei,Area Preopticas,Area, Lateral Preoptic,Area, Medial Preoptic,Area, Preoptic,Areas, Lateral Preoptic,Areas, Medial Preoptic,Areas, Preoptic,Lateral Preoptic Areas,Medial Preoptic Areas,Nuclei, Preoptic,Nucleus, Preoptic,Preoptic Area, Lateral,Preoptic Area, Medial,Preoptic Areas,Preoptic Areas, Lateral,Preoptic Areas, Medial,Preoptic Nucleus,Preoptica, Area,Preopticas, Area
D001833	Body Temperature Regulation	The processes of heating and cooling that an organism uses to control its temperature.	Heat Loss,Thermoregulation,Regulation, Body Temperature,Temperature Regulation, Body,Body Temperature Regulations,Heat Losses,Loss, Heat,Losses, Heat,Regulations, Body Temperature,Temperature Regulations, Body,Thermoregulations
D004372	Ducks	A water bird in the order Anseriformes (subfamily Anatinae (true ducks)) with a broad blunt bill, short legs, webbed feet, and a waddling gait.	Duck
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia