In order to evaluate the applying effect of MDIC implant-magnetic attachments on oral and maxillofacial prostheses, 38 patients, whose oral and maxillofacial defects had been restored with implant-magnetic attachments prostheses, were followed up for 1-4 years. The effects were evaluated by the measurement of the retentive force of the prostheses, X-ray and clinical examination. The results show: the successful rate of the restoration was 94.7%; two sets implant-magnetic attachments could offer an average of 14.7 N retentive force for lower complete dentures, which could meet various functional needs of the prostheses, but magnetic retentive force decreased as the applying time goes on the magnetic retainers should be changed after two years; negative rate of bone absorption on implant-bone surface was 92.6%; negative rate of gingival inflammation was 91.3%. The implant-magnetic attachments offer realize reliable retention, don't transmit lateral force to implants. Patients can insert and remove the prostheses and clean the implants and defect cavities conveniently. The above advantages are benefit to tissue health and functions of the prostheses. So, implant-magnetic attachments can be used in the restoration of various oral and maxillofacial defects.