-transparent.png){kind=logo}
The rates of tryptophanyl-tRNA formation catalyzed by beef pancreas tryptophanyl-tRNA synthetase were measured in a concentration range of each substrate (tryptophan, ATP and yeast tRNATrp) and also in the presence of various concentrations of substrate analogues (tryptamine and alpha,beta-methylene analogue of ATP) concentrations. The data obtained were compared with the kinetic equations which described various possible mechanisms of the reaction. The comparison of the mechanisms was based on the calculation of relative probabilities of each hypothesis the efficiency of which was demonstrated earlier. The calculations have shown that two mechanisms according to which the intermediate enzyme-aminoacyl-adenylate complex formation involves the enzyme-aminoacyl-tRNA complex are the most probable ones.
L L Kochkina, and
V Z Akhverdian, and
L L Kiselev, and
V V Zinov'ev, and
E G Malygin
September 1976,
European journal of biochemistry,
L L Kochkina, and
V Z Akhverdian, and
L L Kiselev, and
V V Zinov'ev, and
E G Malygin
January 1987,
Molekuliarnaia biologiia,
L L Kochkina, and
V Z Akhverdian, and
L L Kiselev, and
V V Zinov'ev, and
E G Malygin
January 1978,
Doklady Akademii nauk SSSR,
L L Kochkina, and
V Z Akhverdian, and
L L Kiselev, and
V V Zinov'ev, and
E G Malygin
July 1973,
Biochimica et biophysica acta,
L L Kochkina, and
V Z Akhverdian, and
L L Kiselev, and
V V Zinov'ev, and
E G Malygin
January 2016,
The Journal of biological chemistry,
L L Kochkina, and
V Z Akhverdian, and
L L Kiselev, and
V V Zinov'ev, and
E G Malygin
March 1986,
Biochemistry,
L L Kochkina, and
V Z Akhverdian, and
L L Kiselev, and
V V Zinov'ev, and
E G Malygin
March 2008,
Nucleic acids research,
L L Kochkina, and
V Z Akhverdian, and
L L Kiselev, and
V V Zinov'ev, and
E G Malygin
January 1972,
Biokhimiia (Moscow, Russia),
L L Kochkina, and
V Z Akhverdian, and
L L Kiselev, and
V V Zinov'ev, and
E G Malygin
January 1978,
Molekuliarnaia biologiia,
L L Kochkina, and
V Z Akhverdian, and
L L Kiselev, and
V V Zinov'ev, and
E G Malygin
January 1993,
Biochimie,
