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Step-by-step therapy of patients with pneumonia and exacerbated chronic bronchitis with amoxyclav (amoxycillin/potassium clavulanate) in a dose of 1.2 g administered intravenously dropwise every 8 hours for the first 2 days of the treatment with subsequent oral use of the drug in a dose of 625 mg thrice a day for 5 days proved to be highly efficient. The recovery and improvement were stated in 19 (95 per cent) out of 20 patients. The adverse reaction (urticaria) was observed in 1 patient. Identical results were recorded in a comparative randomized trial with the use of cefotaxime in a dose of 1.0 g intramuscularly every 8 hours for 7 days. The pharmacoeconomic estimate showed the expediency of the step-by-step therapy with the use of amoxycillin/potassium clavulanate.
V E Nonikov, and
T D Konstantinova, and
N I Lenkova, and
V I Minaev, and
L A Ritchik
September 1983,
Lancet (London, England),
V E Nonikov, and
T D Konstantinova, and
N I Lenkova, and
V I Minaev, and
L A Ritchik
January 1997,
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic],
V E Nonikov, and
T D Konstantinova, and
N I Lenkova, and
V I Minaev, and
L A Ritchik
February 1990,
The Journal of antimicrobial chemotherapy,
V E Nonikov, and
T D Konstantinova, and
N I Lenkova, and
V I Minaev, and
L A Ritchik
March 1986,
The Journal of antimicrobial chemotherapy,
V E Nonikov, and
T D Konstantinova, and
N I Lenkova, and
V I Minaev, and
L A Ritchik
October 1994,
Journal of clinical pharmacy and therapeutics,
V E Nonikov, and
T D Konstantinova, and
N I Lenkova, and
V I Minaev, and
L A Ritchik
November 1989,
The Journal of antimicrobial chemotherapy,
V E Nonikov, and
T D Konstantinova, and
N I Lenkova, and
V I Minaev, and
L A Ritchik
January 1999,
International journal of clinical practice,
V E Nonikov, and
T D Konstantinova, and
N I Lenkova, and
V I Minaev, and
L A Ritchik
February 1985,
The Veterinary record,
V E Nonikov, and
T D Konstantinova, and
N I Lenkova, and
V I Minaev, and
L A Ritchik
August 1986,
The Journal of antimicrobial chemotherapy,
V E Nonikov, and
T D Konstantinova, and
N I Lenkova, and
V I Minaev, and
L A Ritchik
March 1988,
Lancet (London, England),
