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Enzyme immunoassay system has been developed for measuring the titers of secretory IgA in secretion from the upper respiratory airways (SURA). Russian ingredients are used. The conjugate includes monoclonal antibodies to heavy chains of human secretory IgA. The sensitivity and specificity of the kit was tested with SURA of normal subjects and patients with influenza. The initial level of specific secretory IgA antibodies detected by the kit clearly correlated with defense from natural influenza infection. The protective concentrations of the antibodies corresponded to at least 1:64 dilutions. The titers of serum and secretory antibodies in convalescents after influenza A or B were virtually the same. The level of secretory antibodies dropped sooner than that of serum antibodies.
A N Naĭkhin, and
S A Donina, and
Iu G Kustikova, and
L G Katorgina, and
L G Rudenko
January 1985,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
A N Naĭkhin, and
S A Donina, and
Iu G Kustikova, and
L G Katorgina, and
L G Rudenko
January 1988,
Trudy Instituta imeni Pastera,
A N Naĭkhin, and
S A Donina, and
Iu G Kustikova, and
L G Katorgina, and
L G Rudenko
July 2020,
Future microbiology,
A N Naĭkhin, and
S A Donina, and
Iu G Kustikova, and
L G Katorgina, and
L G Rudenko
April 2009,
Revue scientifique et technique (International Office of Epizootics),
A N Naĭkhin, and
S A Donina, and
Iu G Kustikova, and
L G Katorgina, and
L G Rudenko
February 1986,
Journal of clinical microbiology,
A N Naĭkhin, and
S A Donina, and
Iu G Kustikova, and
L G Katorgina, and
L G Rudenko
January 1988,
Laboratornoe delo,
A N Naĭkhin, and
S A Donina, and
Iu G Kustikova, and
L G Katorgina, and
L G Rudenko
January 1989,
Current topics in microbiology and immunology,
A N Naĭkhin, and
S A Donina, and
Iu G Kustikova, and
L G Katorgina, and
L G Rudenko
January 1984,
Voprosy virusologii,
A N Naĭkhin, and
S A Donina, and
Iu G Kustikova, and
L G Katorgina, and
L G Rudenko
January 2010,
Igiene e sanita pubblica,
A N Naĭkhin, and
S A Donina, and
Iu G Kustikova, and
L G Katorgina, and
L G Rudenko
June 1990,
Journal of clinical microbiology,
