[The influence of ricin on the course of experimental infections of mice with Trichinella spiralis]. 1997

K Karmańska, and M Houszka, and A Widyma, and E Stefaniak
Instytut Parazytologii PAN im. W. Stefańskiego, Wrocław.

Mice received 5 ng of ricin 24 hours after infection (experiment I) or 1 ng of ricin twice, 24 hours and 17 days of infection (experiment II). Animals were killed in 7, 14, 21, 28, 35, 42 and 60 days after infection. In the jejunum and masseter muscle sections, CD4+ and CD8+ lymphocytes, mast cells and eosinophils were studied. Heavy suppression of CD8+ lymphocytes, strong eosinophils and less pronounced mast cells stimulation was observed in the jejunum of mice received ricin (experiment I). Worm expulsion in intestine was faster than in the control (opposite results in experiment II). The composition of cells infiltration in the muscle was in both experiments similar to the control, however, fewer CD4+ lymphocytes were observed in larva capsule and there were fewer muscle larvae. Therefore CD8+ cells are believed to take part in restricting only the muscle stage of trichinellosis.

UI MeSH Term Description Entries
D007411 Intestinal Diseases, Parasitic Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS. Parasitic Intestinal Diseases,Disease, Parasitic Intestinal,Diseases, Parasitic Intestinal,Intestinal Disease, Parasitic,Parasitic Intestinal Disease
D007583 Jejunum The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum. Jejunums
D007814 Larva Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals. Maggots,Tadpoles,Larvae,Maggot,Tadpole
D008297 Male Males
D008406 Masseter Muscle A masticatory muscle whose action is closing the jaws. Masseter Muscles,Muscle, Masseter,Muscles, Masseter
D008407 Mast Cells Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR. Basophils, Tissue,Basophil, Tissue,Cell, Mast,Cells, Mast,Mast Cell,Tissue Basophil,Tissue Basophils
D008815 Mice, Inbred Strains Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation. Inbred Mouse Strains,Inbred Strain of Mice,Inbred Strain of Mouse,Inbred Strains of Mice,Mouse, Inbred Strain,Inbred Mouse Strain,Mouse Inbred Strain,Mouse Inbred Strains,Mouse Strain, Inbred,Mouse Strains, Inbred,Strain, Inbred Mouse,Strains, Inbred Mouse
D004334 Drug Administration Schedule Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience. Administration Schedule, Drug,Administration Schedules, Drug,Drug Administration Schedules,Schedule, Drug Administration,Schedules, Drug Administration
D004804 Eosinophils Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin. Eosinophil
D006790 Host-Parasite Interactions The relationship between an invertebrate and another organism (the host), one of which lives at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically. Host-Parasite Relations,Parasite-Host Relations,Host-Parasite Relationship,Parasite-Host Interactions,Host Parasite Interactions,Host Parasite Relations,Host Parasite Relationship,Host-Parasite Interaction,Host-Parasite Relation,Host-Parasite Relationships,Interaction, Host-Parasite,Interaction, Parasite-Host,Interactions, Host-Parasite,Interactions, Parasite-Host,Parasite Host Interactions,Parasite Host Relations,Parasite-Host Interaction,Parasite-Host Relation,Relation, Host-Parasite,Relation, Parasite-Host,Relations, Host-Parasite,Relations, Parasite-Host,Relationship, Host-Parasite,Relationships, Host-Parasite

Related Publications

K Karmańska, and M Houszka, and A Widyma, and E Stefaniak
June 1990, Canadian journal of veterinary research = Revue canadienne de recherche veterinaire,
K Karmańska, and M Houszka, and A Widyma, and E Stefaniak
April 1972, Experimental parasitology,
K Karmańska, and M Houszka, and A Widyma, and E Stefaniak
January 1970, Journal of helminthology,
K Karmańska, and M Houszka, and A Widyma, and E Stefaniak
January 1992, Wiadomosci parazytologiczne,
K Karmańska, and M Houszka, and A Widyma, and E Stefaniak
January 1979, Wiadomosci parazytologiczne,
K Karmańska, and M Houszka, and A Widyma, and E Stefaniak
January 1978, Wiadomosci parazytologiczne,
K Karmańska, and M Houszka, and A Widyma, and E Stefaniak
October 1955, The Journal of parasitology,
K Karmańska, and M Houszka, and A Widyma, and E Stefaniak
January 2006, Wiadomosci parazytologiczne,
K Karmańska, and M Houszka, and A Widyma, and E Stefaniak
January 1980, Bulletin de l'Academie polonaise des sciences. Serie des sciences biologiques,
K Karmańska, and M Houszka, and A Widyma, and E Stefaniak
April 1987, Experimental parasitology,
Copied contents to your clipboard!