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Hemodynamics and blood gases were measured before and 15 minutes after small (10 mg/70 kg) doses of intravenously administered morphine in two groups of patients having open heart surgery. In one group, the study was undertaken after median sternotomy but before perfusion. The other group had been in the intensive care unit for approximately 1 hour. No changes were found in either group in cardiac index, atrial pressures, arterial pressure, or blood gas variables. However, mean systemic vascular resistance decreased from 41.5 to 35.4 after morphine was given postoperatively. Hence, hemodynamically, morphine is a safe drug if given in small doses for pain relief and sedation early after open heart surgery.
E A Moffitt, and
S Tarhan, and
R Rodriguez, and
D A Barnhorst, and
J R Pluth
June 1992,
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E A Moffitt, and
S Tarhan, and
R Rodriguez, and
D A Barnhorst, and
J R Pluth
December 1989,
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E A Moffitt, and
S Tarhan, and
R Rodriguez, and
D A Barnhorst, and
J R Pluth
October 1978,
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E A Moffitt, and
S Tarhan, and
R Rodriguez, and
D A Barnhorst, and
J R Pluth
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E A Moffitt, and
S Tarhan, and
R Rodriguez, and
D A Barnhorst, and
J R Pluth
September 1972,
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E A Moffitt, and
S Tarhan, and
R Rodriguez, and
D A Barnhorst, and
J R Pluth
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E A Moffitt, and
S Tarhan, and
R Rodriguez, and
D A Barnhorst, and
J R Pluth
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Anesthesia and analgesia,
E A Moffitt, and
S Tarhan, and
R Rodriguez, and
D A Barnhorst, and
J R Pluth
September 1964,
Wiener klinische Wochenschrift,
E A Moffitt, and
S Tarhan, and
R Rodriguez, and
D A Barnhorst, and
J R Pluth
December 1970,
Schweizerische medizinische Wochenschrift,
E A Moffitt, and
S Tarhan, and
R Rodriguez, and
D A Barnhorst, and
J R Pluth
June 1987,
The Journal of thoracic and cardiovascular surgery,
