Male and female dental disease frequencies were compared to test the hypothesis of differential stress levels between the sexes in the late Medieval population from Nova Raca, Croatia. The following categories of dental disease were compared: alveolar bone pathology defined by the presence of periodontal or periapical abscesses or antemortem tooth loss, caries, hypoplastic defects in the enamel and occlusal surface wear. The results show clear gender differences in the frequencies of alveolar bone pathology, carious lesions and occlusal surface wear. In all cases males exhibited significantly greater frequencies. Further analyses indicated that these differences were related to younger (15-29 years) adults and to the upper jaw. Together with paleodemographic data and the fact that females exhibited higher frequencies of enamel defects, this dichotomy in dental disease frequencies is interpreted as the result of a culturally imposed defensive mechanism which selectively buffered young males from malnutrition, exposing them at the same time to higher levels of cariogenic food and thus to higher frequencies of carious lesions and alveolar bone disease.