Microsporidial keratoconjunctivitis in a patient without human immunodeficiency virus infection. 1997

B E Silverstein, and E T Cunningham, and T P Margolis, and V Cevallos, and I G Wong
Francis I. Proctor Foundation, University of California, San Francisco 94122-0944, USA.

OBJECTIVE To describe a case of microsporidial keratoconjunctivitis in a patient without human immunodeficiency virus (HIV) infection. METHODS Case report. An epithelial corneal scraping from a woman with chronic bilateral keratoconjunctivitis was evaluated by Giemsa stain. RESULTS Giemsa stain of an epithelial corneal scraping disclosed intracellular and extracellular spores characteristic of microsporidia. An HIV enzyme-linked immunosorbent assay (ELISA) test was negative. The signs and symptoms of the bilateral keratoconjunctivitis resolved after treatment with albendazole. CONCLUSIONS Microsporidia may cause a chronic epithelial keratoconjunctivitis in the absence of HIV infection.

UI MeSH Term Description Entries
D007637 Keratoconjunctivitis Simultaneous inflammation of the cornea and conjunctiva. Keratoconjunctivitides
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000871 Anthelmintics Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal. Anthelmintic,Antihelmintic,Vermifuge,Vermifuges,Antihelmintics
D014792 Visual Acuity Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast. Acuities, Visual,Acuity, Visual,Visual Acuities
D015766 Albendazole A benzimidazole broad-spectrum anthelmintic structurally related to MEBENDAZOLE that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38) Albendazole Monohydrochloride,Albendoral,Albenza,Andazol,Bendapar,Bilutac,Digezanol,Disthelm,Endoplus,Eskazole,Gascop,Lurdex,Mediamix V Disthelm,Metiazol,SK&F-62979,SKF-62979,Valbazen,Zentel,Monohydrochloride, Albendazole,SK&F 62979,SK&F62979,SKF 62979,SKF62979
D015822 Eye Infections, Parasitic Mild to severe infections of the eye and its adjacent structures (adnexa) by adult or larval protozoan or metazoan parasites. Ocular Infections, Parasitic,Parasitic Eye Infections,Eye Infection, Parasitic,Infection, Parasitic Eye,Infection, Parasitic Ocular,Infections, Parasitic Eye,Infections, Parasitic Ocular,Ocular Infection, Parasitic,Parasitic Eye Infection,Parasitic Ocular Infection,Parasitic Ocular Infections
D016816 Microsporida An order of parasitic FUNGI found mostly in ARTHROPODS; FISHES; and in some VERTEBRATES including humans. It comprises two suborders: Pansporoblastina and APANSPOROBLASTINA. Microsporidas

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