Biomaterial Database

Effects of the tol mutation on allelic interactions at het loci in Neurospora crassa. 1997

J F Leslie, and C T Yamashiro

Department of Plant Pathology, Throckmorton Plant Sciences Center, Kansas State University, Manhattan 66506-5502, USA. jfl@plantpath.ksu.edu

A mutant at the tol locus of Neurospora crassa can suppress heterokaryon (vegetative) incompatibility associated with differences at the mating-type locus. We tested the ability of this allele to suppress the vegetative incompatibility reactions that can occur when strains differ at one of nine het loci (het-C, -D, -E, -5, -6, -7, -8, -9, and -10). We found no cases in which the tol mutant suppresses a heteroallelic het locus interaction. Thus, the interaction(s) that leads to vegetative incompatibility because of differences at the mating-type locus is distinct from the interaction(s) that leads to vegetative incompatibility because of differences at any of these nine het loci.

UI	MeSH Term	Description	Entries
D009154	Mutation	Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.	Mutations
D009492	Neurospora crassa	A species of ascomycetous fungi of the family Sordariaceae, order SORDARIALES, much used in biochemical, genetic, and physiologic studies.	Chrysonilia crassa
D003433	Crosses, Genetic	Deliberate breeding of two different individuals that results in offspring that carry part of the genetic material of each parent. The parent organisms must be genetically compatible and may be from different varieties or closely related species.	Cross, Genetic,Genetic Cross,Genetic Crosses
D005656	Fungal Proteins	Proteins found in any species of fungus.	Fungal Gene Products,Fungal Gene Proteins,Fungal Peptides,Gene Products, Fungal,Yeast Proteins,Gene Proteins, Fungal,Peptides, Fungal,Proteins, Fungal
D005800	Genes, Fungal	The functional hereditary units of FUNGI.	Fungal Genes,Fungal Gene,Gene, Fungal
D016153	Genes, Suppressor	Genes that have a suppressor allele or suppressor mutation (SUPPRESSION, GENETIC) which cancels the effect of a previous mutation, enabling the wild-type phenotype to be maintained or partially restored. For example, amber suppressors cancel the effect of an AMBER NONSENSE MUTATION.	Amber Suppressor Genes,Frameshift Suppressor Genes,Genes, Amber Suppressor,Genes, Frameshift Suppressor,Genes, Nonsense Mutation Suppressor,Genes, Ochre Suppressor,Genes, Second-Site Suppressor,Nonsense Mutation Suppressor Genes,Ochre Suppressor Genes,Second-Site Suppressor Genes,Genes, Opal Suppressor,Suppressor Genes,Amber Suppressor Gene,Frameshift Suppressor Gene,Gene, Amber Suppressor,Gene, Frameshift Suppressor,Gene, Ochre Suppressor,Gene, Opal Suppressor,Gene, Second-Site Suppressor,Gene, Suppressor,Genes, Second Site Suppressor,Ochre Suppressor Gene,Opal Suppressor Gene,Opal Suppressor Genes,Second Site Suppressor Genes,Second-Site Suppressor Gene,Suppressor Gene,Suppressor Gene, Amber,Suppressor Gene, Frameshift,Suppressor Gene, Ochre,Suppressor Gene, Opal,Suppressor Gene, Second-Site,Suppressor Genes, Amber,Suppressor Genes, Frameshift,Suppressor Genes, Ochre,Suppressor Genes, Opal,Suppressor Genes, Second-Site
D049770	Genes, Mating Type, Fungal	Fungal genes that mostly encode TRANSCRIPTION FACTORS. In some FUNGI they also encode PHEROMONES and PHEROMONE RECEPTORS. The transcription factors control expression of specific proteins that give a cell its mating identity. Opposite mating type identities are required for mating.	Fungal Mating-Type Genes,Genes, Fungal Mating Type,Mating Type, Fungal,Fungal Mating Type,Fungal Mating Type Genes,Fungal Mating Types,Fungal Mating-Type Gene,Gene, Fungal Mating-Type,Genes, Fungal Mating-Type,Mating Types, Fungal,Mating-Type Gene, Fungal,Mating-Type Genes, Fungal,Type, Fungal Mating,Types, Fungal Mating