Spinal anesthesia: bupivacaine versus tetracaine. 1976

E A Pflug, and G M Aasheim, and H A Beck

The clinical effects of equal hyperbaric doses of bupivacaine HCl and tetracaine HCl were studied and compared in 99 adult men undergoing spinal anesthesia for similar surgical procedures. The spinal anesthetic agents were used in random order in various dosages. Comparisons were made of (1) amount of anesthetic agent used, (2) elapsed time for onset of analgesia, (3) elapsed time for obtaining maximum anesthesia, (4) cephalad dermatome level of anesthesia, (5) incidence of motor blockade, and (6) duration of anesthesia. Results with the 2 drugs in equal dose, volume, and specific gravity were almost identical. However, tetracaine provided a motor block in a significantly greater number of patients than did pubivacaine (100 versus 42%, rho less than 0.001) when both drugs were used at the 9.75-mg dose level.

UI MeSH Term Description Entries
D008297 Male Males
D002045 Bupivacaine A widely used local anesthetic agent. 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide,Bupivacain Janapharm,Bupivacain-RPR,Bupivacaina Braun,Bupivacaine Anhydrous,Bupivacaine Carbonate,Bupivacaine Hydrochloride,Bupivacaine Monohydrochloride, Monohydrate,Buvacaina,Carbostesin,Dolanaest,Marcain,Marcaine,Sensorcaine,Svedocain Sin Vasoconstr,Bupivacain RPR
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000775 Anesthesia, Spinal Procedure in which an anesthetic is injected directly into the spinal cord. Anesthesias, Spinal,Spinal Anesthesia,Spinal Anesthesias
D013748 Tetracaine A potent local anesthetic of the ester type used for surface and spinal anesthesia. Tetrakain,Amethocaine,Ametop,Dicaine,Pantocaine,Pontocaine,Tetracaine Monohydrochloride,Tetrracaine Hydrochloride,Hydrochloride, Tetrracaine
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

Related Publications

E A Pflug, and G M Aasheim, and H A Beck
October 1980, Anesthesia and analgesia,
E A Pflug, and G M Aasheim, and H A Beck
September 1989, Anesthesia and analgesia,
E A Pflug, and G M Aasheim, and H A Beck
January 1977, Acta anaesthesiologica Scandinavica,
E A Pflug, and G M Aasheim, and H A Beck
January 1998, Regional anesthesia and pain medicine,
E A Pflug, and G M Aasheim, and H A Beck
January 1997, Regional anesthesia,
E A Pflug, and G M Aasheim, and H A Beck
January 2002, Anesthesia and analgesia,
E A Pflug, and G M Aasheim, and H A Beck
June 1983, Acta anaesthesiologica Scandinavica,
E A Pflug, and G M Aasheim, and H A Beck
September 1988, Anesthesia and analgesia,
E A Pflug, and G M Aasheim, and H A Beck
January 2003, Journal of anesthesia,
Copied contents to your clipboard!