BIOMAT Database Logo BIOMAT Database Logo

Central pontine myelinolysis and medullary myelinolysis. 1976

B S Bhagavan, and J A Wagner, and J Juanteguy

Central pontine myelinolysis (CPM) is a rare, acute, and uniformly fatal demyelinative process that involves the pons almost exclusively. Three cases diagnosed at autopsy illustrate the characteristic clinical course and pathologic features of CPM. A unique extrapontine location of a similar process is noted in the medulla of a 6-year-old girl. The term "medullary myelinolysis" is a descriptive designation for demyelination that occurs predominantly in this area. The clinical and pathologic features of CPM are reviewed in detail, together with a brief review of theories of metabolic, nutritional, vascular, and endogenous and exogenous toxic factors that act either singly or in concert in the cause and pathogenesis of CPM.

UI MeSH Term Description Entries
D008297 Male Males
D008526 Medulla Oblongata The lower portion of the BRAIN STEM. It is inferior to the PONS and anterior to the CEREBELLUM. Medulla oblongata serves as a relay station between the brain and the spinal cord, and contains centers for regulating respiratory, vasomotor, cardiac, and reflex activities. Accessory Cuneate Nucleus,Ambiguous Nucleus,Arcuate Nucleus of the Medulla,Arcuate Nucleus-1,External Cuneate Nucleus,Lateral Cuneate Nucleus,Nucleus Ambiguus,Ambiguus, Nucleus,Arcuate Nucleus 1,Arcuate Nucleus-1s,Cuneate Nucleus, Accessory,Cuneate Nucleus, External,Cuneate Nucleus, Lateral,Medulla Oblongatas,Nucleus, Accessory Cuneate,Nucleus, Ambiguous,Nucleus, External Cuneate,Nucleus, Lateral Cuneate
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009836 Oligodendroglia A class of large neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal (not the same as SATELLITE CELLS, PERINEURONAL of GANGLIA) according to their location. They form the insulating MYELIN SHEATH of axons in the central nervous system. Interfascicular Oligodendroglia,Oligodendrocytes,Perineuronal Oligodendroglia,Perineuronal Satellite Oligodendroglia Cells,Perivascular Oligodendroglia,Satellite Cells, Perineuronal, Oligodendroglia,Perineuronal Satellite Oligodendrocytes,Interfascicular Oligodendroglias,Oligodendrocyte,Oligodendrocyte, Perineuronal Satellite,Oligodendrocytes, Perineuronal Satellite,Oligodendroglia, Interfascicular,Oligodendroglia, Perineuronal,Oligodendroglia, Perivascular,Perineuronal Satellite Oligodendrocyte,Satellite Oligodendrocyte, Perineuronal,Satellite Oligodendrocytes, Perineuronal
D011149 Pons The front part of the hindbrain (RHOMBENCEPHALON) that lies between the MEDULLA and the midbrain (MESENCEPHALON) ventral to the cerebellum. It is composed of two parts, the dorsal and the ventral. The pons serves as a relay station for neural pathways between the CEREBELLUM to the CEREBRUM. Pons Varolii,Ponte,Pons Varolius,Pontes,Varolii, Pons,Varolius, Pons
D011604 Psychoses, Alcoholic A group of mental disorders associated with organic brain damage and caused by poisoning from alcohol. Alcoholic Psychoses
D001927 Brain Diseases Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. Intracranial Central Nervous System Disorders,Brain Disorders,CNS Disorders, Intracranial,Central Nervous System Disorders, Intracranial,Central Nervous System Intracranial Disorders,Encephalon Diseases,Encephalopathy,Intracranial CNS Disorders,Brain Disease,Brain Disorder,CNS Disorder, Intracranial,Encephalon Disease,Encephalopathies,Intracranial CNS Disorder
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D003300 Copper A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. Copper-63,Copper 63

Related Publications

B S Bhagavan, and J A Wagner, and J Juanteguy
Central pontine myelinolysis central pontine myelinolysis manifesting with massive myoclonus.
July 2004, Pediatric neurology,
B S Bhagavan, and J A Wagner, and J Juanteguy
Central pontine myelinolysis.
October 1969, Neurology,
B S Bhagavan, and J A Wagner, and J Juanteguy
Central pontine myelinolysis.
March 1981, Postgraduate medical journal,
B S Bhagavan, and J A Wagner, and J Juanteguy
Central pontine myelinolysis.
May 2013, The Indian journal of medical research,
B S Bhagavan, and J A Wagner, and J Juanteguy
Central pontine myelinolysis.
January 1974, Neuropatologia polska,
B S Bhagavan, and J A Wagner, and J Juanteguy
Central pontine myelinolysis.
January 1973, Proceedings of the Australian Association of Neurologists,
B S Bhagavan, and J A Wagner, and J Juanteguy
Central pontine myelinolysis.
March 1976, New York state journal of medicine,
B S Bhagavan, and J A Wagner, and J Juanteguy
[Central pontine myelinolysis].
April 1990, RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin,
B S Bhagavan, and J A Wagner, and J Juanteguy
[Central pontine myelinolysis].
January 2009, Fortschritte der Neurologie-Psychiatrie,
B S Bhagavan, and J A Wagner, and J Juanteguy
CENTRAL PONTINE MYELINOLYSIS.
August 1964, Journal of neurology, neurosurgery, and psychiatry,
Copied contents to your clipboard!