[Transitory acantholytic dermatosis (Grover's disease) in sarcoptic scabies infection]. 1997

E Köstler
Hautklinik, Krankenhauses Dresden-Friedrichstadt-Städtisches Klinikum.

An eighty-two year old patient had scabies and transient acantholytic dermatosis (TAD, Grover's disease) at the same time. Persistent itching papules after lindane therapy finally led us to the microscopic diagnosis of TAD. Different trigger mechanisms can apparently induce the typical acantholysis. In addition to solar radiation, tumors and tumor therapy-dependent conditions, cutaneous infections have been implicated reports (Demodex folliculorum, Malassezia furfur) as causes of TAD. This may be the first report about a relationship between TAD and mite infection with Sarcoptes scabiei.

UI MeSH Term Description Entries
D007306 Insecticides Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics. Insecticide
D008297 Male Males
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000051 Acantholysis Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris (see PEMPHIGUS) and DARIER DISEASE. Acantholyses
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001556 Hexachlorocyclohexane Any of several polyhalogenated organic compounds consisting of a six-carbon ring with one chlorine and one hydrogen attached to each carbon. Benzene Hexachloride,Lindane,gamma-Benzene Hexachloride,BHC Insecticide,Delitex,Epsilon-hexachlorocyclohexane,Eta-hexachlorocyclohexane,Gamma-666,Gammexane,Hexachlorane,Jacutin,Kwell,PMS-Lindane,Scabecid,Scabene,Scabisan,Tetocid,Zeta-hexachlorocyclohexane,gamma-HCH,gamma-Hexachlorocyclohexane,Epsilon hexachlorocyclohexane,Eta hexachlorocyclohexane,Gamma 666,Hexachloride, Benzene,Hexachloride, gamma-Benzene,Insecticide, BHC,PMS Lindane,Zeta hexachlorocyclohexane,gamma Benzene Hexachloride,gamma HCH,gamma Hexachlorocyclohexane
D012520 Sarcoptes scabiei A species of mite that causes SCABIES in humans and sarcoptic mange in other animals. Specific variants of S. scabiei exist for humans and animals, but many have the ability to cross species and cause disease. Sarcoptes scabieus,scabieus, Sarcoptes
D012532 Scabies A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body. Mange, Sarcoptic,Sarcoptic Mange

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