Biomaterial Database

Contrast sensitivity for stationary and drifting spatial frequency gratings in positive- and negative-symptom schizophrenia. 1998

W L Slaghuis

Department of Psychology, University of Tasmania, Hobart, Australia.

To investigate the transient channel deficit hypothesis in schizophrenia, the authors measured the contrast sensitivity for stationary and drifting gratings in groups with positive- and negative-symptom schizophrenia. The negative-symptom group showed a significant reduction in contrast sensitivity for stationary and drifting gratings at low, medium, and high spatial frequencies in comparison to the control group. There were no differences in contrast sensitivity between the control and positive-symptom groups for stationary and drifting gratings at low-spatial frequencies, but there were significant reductions at medium and high spatial frequencies. The results are consistent with a disorder in both sustained and transient channels in negative-symptom schizophrenia and a disorder in sustained channels in positive-symptom schizophrenia.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009039	Motion Perception	The real or apparent movement of objects through the visual field.	Movement Perception,Perception, Motion,Perception, Movement
D010364	Pattern Recognition, Visual	Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs.	Recognition, Visual Pattern,Visual Pattern Recognition
D011569	Psychiatric Status Rating Scales	Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.	Factor Construct Rating Scales (FCRS),Katz Adjustment Scales,Lorr's Inpatient Multidimensional Psychiatric Rating Scale,Wittenborn Scales,Edinburgh Postnatal Depression Scale,Mini International Neuropsychiatric Interview
D003702	Delusions	A false belief regarding the self or persons or objects outside the self that persists despite the facts, and is not considered tenable by one's associates.	Delusion
D003863	Depression	Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.	Depressive Symptoms,Emotional Depression,Depression, Emotional,Depressive Symptom,Symptom, Depressive
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D001143	Arousal	Cortical vigilance or readiness of tone, presumed to be in response to sensory stimulation via the reticular activating system.	Vigilance, Cortical,Arousals,Cortical Vigilance