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This study was designed to analyze the complex morphologic and functional effects of dialysis solutions on peritoneum in a rat model on chronic peritoneal dialysis. Peritoneal catheters were inserted into 10 male, Wistar rats and the animals were dialyzed twice daily for 4 weeks with 4.25% Dianeal. During the study we observed two opposite effects: healing of the peritoneum after catheter implantation--decreased cell count in dialysate, decreased permeability of the peritoneum to glucose and total protein, increased volume of drained dialysate; and damage to the membrane due to its exposure to peritoneal dialysis solution--increased hyaluronic acid levels in dialysate, a tendency of the peritoneum to thicken when compared to non-dialyzed animals. Our rat model of CAPD may be used for quantitative and qualitative assessment of the effects of peritoneal dialysis solution on the peritoneum during chronic dialysis.
K Wieczorowska-Tobis, and
K Korybalska, and
A Polubinska, and
M Radkowski, and
A Breborowicz, and
D G Oreopoulos
May 1996,
American journal of kidney diseases : the official journal of the National Kidney Foundation,
K Wieczorowska-Tobis, and
K Korybalska, and
A Polubinska, and
M Radkowski, and
A Breborowicz, and
D G Oreopoulos
January 1993,
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
K Wieczorowska-Tobis, and
K Korybalska, and
A Polubinska, and
M Radkowski, and
A Breborowicz, and
D G Oreopoulos
January 1993,
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
K Wieczorowska-Tobis, and
K Korybalska, and
A Polubinska, and
M Radkowski, and
A Breborowicz, and
D G Oreopoulos
January 1993,
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
K Wieczorowska-Tobis, and
K Korybalska, and
A Polubinska, and
M Radkowski, and
A Breborowicz, and
D G Oreopoulos
March 2001,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
K Wieczorowska-Tobis, and
K Korybalska, and
A Polubinska, and
M Radkowski, and
A Breborowicz, and
D G Oreopoulos
October 1996,
Advances in renal replacement therapy,
K Wieczorowska-Tobis, and
K Korybalska, and
A Polubinska, and
M Radkowski, and
A Breborowicz, and
D G Oreopoulos
January 2000,
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
K Wieczorowska-Tobis, and
K Korybalska, and
A Polubinska, and
M Radkowski, and
A Breborowicz, and
D G Oreopoulos
January 2000,
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
K Wieczorowska-Tobis, and
K Korybalska, and
A Polubinska, and
M Radkowski, and
A Breborowicz, and
D G Oreopoulos
January 1995,
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
K Wieczorowska-Tobis, and
K Korybalska, and
A Polubinska, and
M Radkowski, and
A Breborowicz, and
D G Oreopoulos
January 1997,
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
