The stone man: myositis (fibrodysplasia) ossificans progressiva. 1998

T Baysal, and N Elmali, and R Kutlu, and O Baysal
Department of Radiology, Inonu University Faculty of Medicine, Turgut Ozal Medical Center Malatya, Turkey.

Myositis ossificans progressiva (MOP) is a rare hereditary connective tissue disorder characterized by progressive ossification of striated muscle and connective tissue associated with pain and disability. It is presumably transmitted as an autosomal dominant defect. Congenital anomalies of the hands and feet are early signs of this disease. Involvement of the spine, hips and extremities lead to the development of the "stone man" with only less than 600 cases reported in the literature. We present a case of MOP with typical muscle ossifications and skeletal malformations.

UI MeSH Term Description Entries
D007091 Image Processing, Computer-Assisted A technique of inputting two-dimensional or three-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer. Biomedical Image Processing,Computer-Assisted Image Processing,Digital Image Processing,Image Analysis, Computer-Assisted,Image Reconstruction,Medical Image Processing,Analysis, Computer-Assisted Image,Computer-Assisted Image Analysis,Computer Assisted Image Analysis,Computer Assisted Image Processing,Computer-Assisted Image Analyses,Image Analyses, Computer-Assisted,Image Analysis, Computer Assisted,Image Processing, Biomedical,Image Processing, Computer Assisted,Image Processing, Digital,Image Processing, Medical,Image Processings, Medical,Image Reconstructions,Medical Image Processings,Processing, Biomedical Image,Processing, Digital Image,Processing, Medical Image,Processings, Digital Image,Processings, Medical Image,Reconstruction, Image,Reconstructions, Image
D007592 Joint Diseases Diseases involving the JOINTS. Arthropathies,Arthropathy,Joint Disease
D008297 Male Males
D009221 Myositis Ossificans A disease characterized by bony deposits or the ossification of muscle tissue. Fibrodysplasia Ossificans Progressiva,Myositis Ossificans Progressiva,Progressive Myositis Ossificans,Progressive Ossifying Myositis
D003238 Connective Tissue Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX. Connective Tissues,Tissue, Connective,Tissues, Connective
D003240 Connective Tissue Diseases A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides. Connective Tissue Disease,Disease, Connective Tissue,Diseases, Connective Tissue
D005532 Foot Deformities, Congenital Alterations or deviations from normal shape or size which result in a disfigurement of the foot occurring at or before birth. Congenital Foot Deformities,Congenital Foot Deformity,Deformities, Congenital Foot,Deformity, Congenital Foot,Foot Deformity, Congenital
D006228 Hand Deformities, Congenital Alterations or deviations from normal shape or size which result in a disfigurement of the hand occurring at or before birth. Congenital Hand Deformities,Congenital Hand Deformity,Deformities, Congenital Hand,Deformity, Congenital Hand,Hand Deformity, Congenital
D006621 Hip Joint The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS. Acetabulofemoral Joint,Acetabulofemoral Joints,Hip Joints,Joint, Acetabulofemoral,Joint, Hip,Joints, Acetabulofemoral,Joints, Hip
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

T Baysal, and N Elmali, and R Kutlu, and O Baysal
October 1984, Alabama medicine : journal of the Medical Association of the State of Alabama,
T Baysal, and N Elmali, and R Kutlu, and O Baysal
July 2012, Joint bone spine,
T Baysal, and N Elmali, and R Kutlu, and O Baysal
December 1994, Seminars in arthritis and rheumatism,
T Baysal, and N Elmali, and R Kutlu, and O Baysal
November 1995, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
T Baysal, and N Elmali, and R Kutlu, and O Baysal
February 1988, Archives francaises de pediatrie,
T Baysal, and N Elmali, and R Kutlu, and O Baysal
June 2022, Clinical rheumatology,
T Baysal, and N Elmali, and R Kutlu, and O Baysal
January 1990, Journal of clinical anesthesia,
T Baysal, and N Elmali, and R Kutlu, and O Baysal
September 1986, Orthopaedic review,
T Baysal, and N Elmali, and R Kutlu, and O Baysal
July 2012, BMJ case reports,
T Baysal, and N Elmali, and R Kutlu, and O Baysal
December 2019, Journal of medical case reports,
Copied contents to your clipboard!