BIOMAT Database Logo BIOMAT Database Logo

Immunoadjuvant effect of inactivated Cryptococcus neoformans. 1997

Z Hubálek
Institute of Landscape Ecology, Academy of Sciences, Brno, Czech Republic.

Cryptococcus neoformans disseminated into the central nervous system (CNS) of intraperitoneally inoculated adult ICR mice, but did not potentiate penetration of concurrently given Bhanja virus (Bunyaviridae) into the CNS. Likewise, Bhanja virus infection did not affect significantly the course of murine cryptococcosis. However, formalin-killed C. neoformans cells non-specifically increased production of antibodies against the virus infection in the animals.

UI MeSH Term Description Entries
D007274 Injections, Intraperitoneal Forceful administration into the peritoneal cavity of liquid medication, nutrient, or other fluid through a hollow needle piercing the abdominal wall. Intraperitoneal Injections,Injection, Intraperitoneal,Intraperitoneal Injection
D008297 Male Males
D008813 Mice, Inbred ICR An inbred strain of mouse that is used as a general purpose research strain, for therapeutic drug testing, and for the genetic analysis of CARCINOGEN-induced COLON CANCER. Mice, Inbred ICRC,Mice, ICR,Mouse, ICR,Mouse, Inbred ICR,Mouse, Inbred ICRC,ICR Mice,ICR Mice, Inbred,ICR Mouse,ICR Mouse, Inbred,ICRC Mice, Inbred,ICRC Mouse, Inbred,Inbred ICR Mice,Inbred ICR Mouse,Inbred ICRC Mice,Inbred ICRC Mouse
D002044 Bunyaviridae Infections Virus diseases caused by the BUNYAVIRIDAE. Bunyavirus Infections,Infections, Bunyaviridae,Infections, Bunyavirus,Oropouche Fever,Oropouche Infection,Oropouche Orthobunyavirus Infection,Oropouche Virus Infection,Orthobunyavirus Infections,Bunyaviridae Infection,Bunyavirus Infection,Oropouche Fevers,Orthobunyavirus Infection,Orthobunyavirus Infection, Oropouche,Virus Infection, Oropouche
D002490 Central Nervous System The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges. Cerebrospinal Axis,Axi, Cerebrospinal,Axis, Cerebrospinal,Central Nervous Systems,Cerebrospinal Axi,Nervous System, Central,Nervous Systems, Central,Systems, Central Nervous
D003455 Cryptococcus neoformans A species of the fungus CRYPTOCOCCUS. Its teleomorph is Filobasidiella neoformans. Blastomyces neoformans,Debaryomyces neoformans,Filobasidiella neoformans,Lipomyces neoformans,Saccharomyces neoformans,Torula neoformans,Torulopsis neoformans,Cryptococcus neoformans var. grubii
D005557 Formaldehyde A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717) Formalin,Formol,Methanal,Oxomethane
D000276 Adjuvants, Immunologic Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. Immunoactivators,Immunoadjuvant,Immunoadjuvants,Immunologic Adjuvant,Immunopotentiator,Immunopotentiators,Immunostimulant,Immunostimulants,Adjuvant, Immunologic,Adjuvants, Immunological,Immunologic Adjuvants,Immunological Adjuvant,Adjuvant, Immunological,Immunological Adjuvants
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000917 Antibody Formation The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS. Antibody Production,Antibody Response,Antibody Responses,Formation, Antibody,Production, Antibody,Response, Antibody,Responses, Antibody

Related Publications

Z Hubálek
[Cryptococcus neoformans and skin. I. Ecology of Cryptococcus neoformans].
August 1969, Giornale italiano di dermatolotia. Minerva dermatologica,
Z Hubálek
[Cryptococcus neoformans, var. neoformans, Cryptococcus neoformans var. gattii, causative agents of cryptococcosis].
January 1987, Bulletin et memoires de l'Academie royale de medecine de Belgique,
Z Hubálek
Cryptococcus neoformans.
September 1961, Canadian journal of medical technology,
Z Hubálek
Cryptococcus neoformans.
December 1998, The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society,
Z Hubálek
Cryptococcus neoformans.
February 2020, Trends in microbiology,
Z Hubálek
Cryptococcus neoformans Meningoencephalitis.
July 2018, The New England journal of medicine,
Z Hubálek
Cryptococcus neoformans meningitis.
December 1959, The Medical journal of Malaya,
Z Hubálek
[Cryptococcus neoformans meningoencephalitis].
May 1984, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
Z Hubálek
Cryptococcus neoformans infection.
September 2002, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society,
Z Hubálek
Cryptococcus neoformans meningitis.
April 1985, The Central African journal of medicine,
Copied contents to your clipboard!