Effect of dopamine on portal blood flow in cirrhotic patients. 1998

N Kaya, and O Yeşildağ, and H Kahraman, and H Boyunağa, and C Demircan, and U Yalçintaş, and S Kapicioğlu
Section of Gastroenterology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.

OBJECTIVE The effects of dopamine infusion on portal blood flow were examined in 12 cirrhotic patients (seven men, five women) in a Child-B group. METHODS Dopamine was administered as an intravenous infusion (2 micrograms kg-1 min-1). RESULTS At 0, 30 and 60 min, portal blood flow, left ventricular systolic and diastolic functions were evaluated using the pulsed doppler method. No significant difference was found between heart rate, blood pressure and parameters demonstrating left ventricular systolic and diastolic functions before and after dopamine infusions. Portal blood flow decreased significantly at 30 and 60 min. Portal blood flow fell from 1802 +/- 88 to 1339 +/- 50 ml min-1 (P < 0.001) at 30 min and to 1121 +/- 60 ml min-1 (P < 0.001) at 60 min. CONCLUSIONS The reducing effects of dopamine on portal blood flow in cirrhotic patients were demonstrated by the pulsed doppler method, which is a noninvasive test.

UI MeSH Term Description Entries
D007262 Infusions, Intravenous The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it. Drip Infusions,Intravenous Drip,Intravenous Infusions,Drip Infusion,Drip, Intravenous,Infusion, Drip,Infusion, Intravenous,Infusions, Drip,Intravenous Infusion
D008102 Liver Circulation The circulation of BLOOD through the LIVER. Hepatic Circulation,Circulation, Liver,Circulation, Hepatic
D008103 Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. Cirrhosis, Liver,Fibrosis, Liver,Hepatic Cirrhosis,Liver Fibrosis,Cirrhosis, Hepatic
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011168 Portal System A system of vessels in which blood, after passing through one CAPILLARY BED, is conveyed through a second set of capillaries before it returns to the systemic circulation. It pertains especially to the hepatic portal system. Portal Systems,System, Portal,Systems, Portal
D004298 Dopamine One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action. Hydroxytyramine,3,4-Dihydroxyphenethylamine,4-(2-Aminoethyl)-1,2-benzenediol,Dopamine Hydrochloride,Intropin,3,4 Dihydroxyphenethylamine,Hydrochloride, Dopamine
D005260 Female Females
D006439 Hemodynamics The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM. Hemodynamic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

N Kaya, and O Yeşildağ, and H Kahraman, and H Boyunağa, and C Demircan, and U Yalçintaş, and S Kapicioğlu
January 1990, Digestion,
N Kaya, and O Yeşildağ, and H Kahraman, and H Boyunağa, and C Demircan, and U Yalçintaş, and S Kapicioğlu
March 2003, The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology,
N Kaya, and O Yeşildağ, and H Kahraman, and H Boyunağa, and C Demircan, and U Yalçintaş, and S Kapicioğlu
September 1986, The Journal of surgical research,
N Kaya, and O Yeşildağ, and H Kahraman, and H Boyunağa, and C Demircan, and U Yalçintaş, and S Kapicioğlu
June 1995, The Italian journal of gastroenterology,
N Kaya, and O Yeşildağ, and H Kahraman, and H Boyunağa, and C Demircan, and U Yalçintaş, and S Kapicioğlu
April 1982, British medical journal (Clinical research ed.),
N Kaya, and O Yeşildağ, and H Kahraman, and H Boyunağa, and C Demircan, and U Yalçintaş, and S Kapicioğlu
February 1991, Journal of clinical pharmacology,
N Kaya, and O Yeşildağ, and H Kahraman, and H Boyunağa, and C Demircan, and U Yalçintaş, and S Kapicioğlu
February 1997, Zhonghua wai ke za zhi [Chinese journal of surgery],
N Kaya, and O Yeşildağ, and H Kahraman, and H Boyunağa, and C Demircan, and U Yalçintaş, and S Kapicioğlu
October 1972, Gut,
N Kaya, and O Yeşildağ, and H Kahraman, and H Boyunağa, and C Demircan, and U Yalçintaş, and S Kapicioğlu
November 1984, Gastroenterology,
N Kaya, and O Yeşildağ, and H Kahraman, and H Boyunağa, and C Demircan, and U Yalçintaş, and S Kapicioğlu
May 1961, Nature,
Copied contents to your clipboard!