Biomaterial Database

Monitoring spinal-cord injury intraoperatively and attempting prognosis by cortical somatosensory evoked potentials: experimental study. 1998

N Shen, and S Wang

Department of Orthopedics, People's Hospital of Hainan Province, Haikou, China.

In order to monitor spinal-cord injury intraoperatively and to evaluate prognosis by cortical somatosensory evoked potentials (CSEP), the spinal-cord function of 42 dogs, whose cords were injured by air-sac pressure or various striking trauma, was monitored by CSEP intraoperatively and 1 to 3 months postoperatively. Although amplitude declined by 100 percent, compared with preoperative readings, spinal-cord injury by air-sac pressure had no lasting effects. If the pressure was removed in a timely fashion, the function of the spinal cord recovered after 1 to 3 months postoperatively. As for the effect of various striking traumas, safe limits, according to intraoperative CSEP monitoring, were that the prolonged P1 wave latency was less than 1.5 times, and that the declining P1-N1 wave amplitude was less than 50 percent. The change in amplitude was quite sensitive and its recovery was earlier than morphologic changes and functional recovery. Results indicated that CSEP monitoring of spinal-cord injury intraoperatively is accurate and reliable and that it can also predict an accurate prognosis for the injured spinal cord in this canine model.

UI	MeSH Term	Description	Entries
D011379	Prognosis	A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.	Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D005073	Evoked Potentials, Somatosensory	The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM.	Somatosensory Evoked Potentials,Evoked Potential, Somatosensory,Somatosensory Evoked Potential
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013119	Spinal Cord Injuries	Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).	Myelopathy, Traumatic,Injuries, Spinal Cord,Post-Traumatic Myelopathy,Spinal Cord Contusion,Spinal Cord Laceration,Spinal Cord Transection,Spinal Cord Trauma,Contusion, Spinal Cord,Contusions, Spinal Cord,Cord Contusion, Spinal,Cord Contusions, Spinal,Cord Injuries, Spinal,Cord Injury, Spinal,Cord Laceration, Spinal,Cord Lacerations, Spinal,Cord Transection, Spinal,Cord Transections, Spinal,Cord Trauma, Spinal,Cord Traumas, Spinal,Injury, Spinal Cord,Laceration, Spinal Cord,Lacerations, Spinal Cord,Myelopathies, Post-Traumatic,Myelopathies, Traumatic,Myelopathy, Post-Traumatic,Post Traumatic Myelopathy,Post-Traumatic Myelopathies,Spinal Cord Contusions,Spinal Cord Injury,Spinal Cord Lacerations,Spinal Cord Transections,Spinal Cord Traumas,Transection, Spinal Cord,Transections, Spinal Cord,Trauma, Spinal Cord,Traumas, Spinal Cord,Traumatic Myelopathies,Traumatic Myelopathy
D016343	Monitoring, Intraoperative	The constant checking on the state or condition of a patient during the course of a surgical operation (e.g., checking of vital signs).	Intraoperative Monitoring