Tuberculous meningitis in a five-week-old infant. 1998

R Watchi, and K Lu, and E Kahlstrom, and R Allison, and A Kovacs
Department of Pediatrics, Women's and Children's Hospital, University of Southern California School of Medicine, Los Angeles, California, USA. RWatchi@pol.net

We present the case of a five-week-old infant with tuberculous meningitis. The contact investigation and a review of the literature helped us differentiate congenital from acquired tuberculous meningitis. Though rare, we with to emphasize the importance of considering tuberculosis in any neonate with meningitis that fails to respond to conventional treatment, particularly in infants living in an environment where tuberculosis is prevalent.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D008297 Male Males
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014390 Tuberculosis, Meningeal A form of bacterial meningitis caused by MYCOBACTERIUM TUBERCULOSIS or rarely MYCOBACTERIUM BOVIS. The organism seeds the meninges and forms microtuberculomas which subsequently rupture. The clinical course tends to be subacute, with progressions occurring over a period of several days or longer. Headache and meningeal irritation may be followed by SEIZURES, cranial neuropathies, focal neurologic deficits, somnolence, and eventually COMA. The illness may occur in immunocompetent individuals or as an OPPORTUNISTIC INFECTION in the ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunodeficiency syndromes. (From Adams et al., Principles of Neurology, 6th ed, pp717-9) Meningitis, Tuberculous,TB Meningitis,Tubercular Meningitis,Tuberculosis Meningitis,Tuberculous Hypertrophic Pachymeningitis,Hypertrophic Pachymeningitides, Tuberculous,Hypertrophic Pachymeningitis, Tuberculous,Meningeal Tuberculoses,Meningeal Tuberculosis,Meningitides, Tubercular,Meningitides, Tuberculosis,Meningitides, Tuberculous,Meningitis, Tubercular,Meningitis, Tuberculosis,Pachymeningitides, Tuberculous Hypertrophic,Pachymeningitis, Tuberculous Hypertrophic,TB Meningitides,Tubercular Meningitides,Tuberculoses, Meningeal,Tuberculosis Meningitides,Tuberculous Hypertrophic Pachymeningitides,Tuberculous Meningitides,Tuberculous Meningitis
D016358 Contact Tracing Identification of those persons (or animals) who have had such an association with an infected person, animal, or contaminated environment as to have had the opportunity to acquire the infection. Close Contact Epidemiology,Communicable Disease Contact Tracing,Contact Investigation,Contact Screening,Index Case Epidemiology,Index Patient Epidemiology,Infectious Disease Contact Tracing,Notification, Partner,PUI Epidemiology,Partner Notification,Patient Zero Epidemiology,Person Under Investigation Epidemiology,Epidemiology, Close Contact,Epidemiology, Index Case,Epidemiology, Index Patient,Epidemiology, PUI,Epidemiology, Patient Zero,Investigation, Contact,Partner Notifications,Screening, Contact,Tracing, Contact

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