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Granulocytic ehrlichiosis in tick-immune guinea pigs. 1998
S Das, and
K Deponte, and
N L Marcantonio, and
J W Ijdo, and
E Hodzic, and
P Katavolos, and
S W Barthold, and
S R Telford, and
F S Kantor, and
E Fikrig
Department of Internal Medicine, Yale University, New Haven, Connecticut 06520-8031, USA.
We investigated whether Ixodes scapularis-mediated host immunity interrupts transmission of the agent of human granulocytic ehrlichiosis (aoHGE) to guinea pigs. Ticks infected with aoHGE readily transmitted aoHGE to tick-immune guinea pigs, despite incomplete tick engorgement and host attachment. Although tick immunity can prevent Lyme borreliosis, protection is not afforded against granulocytic ehrlichiosis.
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