The prevalence of toxoplasma antibodies in pregnant Nigerian women and the occurrence of stillbirth and congenital malformation. 1996

M O Onadeko, and D H Joynson, and R A Payne, and J Francis
Department of Preventive and Social Medicine, University College Hospital, Ibadan, Nigeria.

Toxoplasma antibody serological tests were carried out using the Dye test on sera of pregnant and postpartum Nigerian women to investigate whether there was any association between the levels of antibody titres and the occurrence of stillbirths and congenital malformations. There was a high prevalence of toxoplasma antibodies in the sera of both pregnant and postpartum women. The prevalence rates for the pregnant women ranged from 72.5% to 88.8% with an overall rate of 75.4%; whilst for the postpartum women, the prevalence rates ranged from 75.0% to 94.4% with an overall rate of 80.5%. The toxoplasma antibody titres of the sera from the live-born babies as well as stillbirths and congenitally malformed babies ranged from 1:16 to 1:1024. The exact role played by toxoplasma in the occurrence of stillbirths and congenital malformation in our area of study is, however, not clear. For future research, it is suggested that larger samples be studied in order to enhance the validity of the findings of the present study.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009549 Nigeria A republic in western Africa, south of NIGER between BENIN and CAMEROON. Its capital is Abuja. Federal Republic of Nigeria
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D005260 Female Females
D005313 Fetal Death Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH. Fetal Mummification,Fetal Demise,Death, Fetal,Deaths, Fetal,Demise, Fetal,Fetal Deaths,Mummification, Fetal
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000013 Congenital Abnormalities Malformations of organs or body parts during development in utero. Birth Defects,Congenital Defects,Deformities,Fetal Anomalies,Fetal Malformations,Abnormalities, Congenital,Defects, Congenital,Abnormality, Congenital,Anomaly, Fetal,Birth Defect,Congenital Abnormality,Congenital Defect,Defect, Birth,Defect, Congenital,Deformity,Fetal Anomaly,Fetal Malformation,Malformation, Fetal
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000913 Antibodies, Protozoan Immunoglobulins produced in a response to PROTOZOAN ANTIGENS. Protozoan Antibodies

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