Biomaterial Database

[Extracorporeal fertilization and cleavage of human oocytes]. 1976

A I Nikitin, and M P Nikolaĭchuk, and E M Kitaev

A method of extracorporeal cultivation and fertilization of human oocytes is described. A special method of selection of active spermatozoa was used. The zygote formed 24-36 hours after the fertilization of oocytes; cleavage of two blastomeres occurred in 36-40 hours. Formation of the four-cell stage embryos was observed in 48 hours. The number of blastomeres reached eight in 60-64 hours and the morula formed in 100-120 hours. The results obtained in this work open opportunities for wide study of physiology and pathology of early human embryonic development.

UI	MeSH Term	Description	Entries
D004622	Embryo, Mammalian	The entity of a developing mammal (MAMMALS), generally from the cleavage of a ZYGOTE to the end of embryonic differentiation of basic structures. For the human embryo, this represents the first two months of intrauterine development preceding the stages of the FETUS.	Embryonic Structures, Mammalian,Mammalian Embryo,Mammalian Embryo Structures,Mammalian Embryonic Structures,Embryo Structure, Mammalian,Embryo Structures, Mammalian,Embryonic Structure, Mammalian,Embryos, Mammalian,Mammalian Embryo Structure,Mammalian Embryonic Structure,Mammalian Embryos,Structure, Mammalian Embryo,Structure, Mammalian Embryonic,Structures, Mammalian Embryo,Structures, Mammalian Embryonic
D004626	Embryology	The study of the development of an organism during the embryonic and fetal stages of life.	Embryologies
D005306	Fertilization	The fusion of a spermatozoon (SPERMATOZOA) with an OVUM thus resulting in the formation of a ZYGOTE.	Conception,Fertilization, Delayed,Fertilization, Polyspermic,Conceptions,Delayed Fertilization,Delayed Fertilizations,Fertilizations,Fertilizations, Delayed,Fertilizations, Polyspermic,Polyspermic Fertilization,Polyspermic Fertilizations
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D066298	In Vitro Techniques	Methods to study reactions or processes taking place in an artificial environment outside the living organism.	In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In