-transparent.png){kind=logo}
The effect of deoxyribonucleoproteid (DNP) solubilization under conditions of the ionic strength of the medium approaching the physiological one depended greatly after the treatment with a mutagen - N-nitroso-N-methylurea (NMU) on the NMU concentration. Apparently, for the change of DNA into a soluble state the critical number of groups in the DNA and protein should be modified. On the basis of the data obtained by circular dichroism and viscosimetry a conclusion was drawn that after the NMU treatment the DNP complex became soluble in the solvents with the ionic strength approaching the physiological one, chiefly as the result of labilization and dissociation of DNA-protein bonds.
A I Gorin, and
A M Serebrianyĭ, and
L V Antonova, and
V K Atkochiunaĭte, and
I G Kharitonenkov
January 2004,
Report on carcinogens : carcinogen profiles,
A I Gorin, and
A M Serebrianyĭ, and
L V Antonova, and
V K Atkochiunaĭte, and
I G Kharitonenkov
May 1978,
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man,
A I Gorin, and
A M Serebrianyĭ, and
L V Antonova, and
V K Atkochiunaĭte, and
I G Kharitonenkov
January 2002,
Report on carcinogens : carcinogen profiles,
A I Gorin, and
A M Serebrianyĭ, and
L V Antonova, and
V K Atkochiunaĭte, and
I G Kharitonenkov
January 1969,
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia,
A I Gorin, and
A M Serebrianyĭ, and
L V Antonova, and
V K Atkochiunaĭte, and
I G Kharitonenkov
April 1969,
Doklady Akademii nauk SSSR,
A I Gorin, and
A M Serebrianyĭ, and
L V Antonova, and
V K Atkochiunaĭte, and
I G Kharitonenkov
January 2011,
Report on carcinogens : carcinogen profiles,
A I Gorin, and
A M Serebrianyĭ, and
L V Antonova, and
V K Atkochiunaĭte, and
I G Kharitonenkov
January 1981,
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia,
A I Gorin, and
A M Serebrianyĭ, and
L V Antonova, and
V K Atkochiunaĭte, and
I G Kharitonenkov
January 1971,
Voprosy onkologii,
A I Gorin, and
A M Serebrianyĭ, and
L V Antonova, and
V K Atkochiunaĭte, and
I G Kharitonenkov
November 1977,
Cancer research,
A I Gorin, and
A M Serebrianyĭ, and
L V Antonova, and
V K Atkochiunaĭte, and
I G Kharitonenkov
February 1997,
Cancer research,
