-transparent.png){kind=logo}
The response of serum gastrin to a meal has been studied in 11 normal subjects and 16 patients with duodenal ulceration. The mean serum gastrin concentration rises after a meal to similar peak values in both normal subjects and duodenal ulcer patients, and fall to basal values with 3 hours in normal subjects. In duodenal ulcer patients the peak concentration is sustained throughout the 3 hour test period, and this response is not affected by the administration of Metiamide. It is concluded that the control of gastrin release is defective in duodenal ulceration, and this may be due to a failure of the antral pH feedback mechanism. Gastrin may be a primary pathogenetic factor in duodenal ulceration.
E L Blair, and
E R Grund, and
J D Reed, and
D J Sanders, and
M H Thompson, and
C W Venables
January 1983,
Acta medica Hungarica,
E L Blair, and
E R Grund, and
J D Reed, and
D J Sanders, and
M H Thompson, and
C W Venables
July 1977,
Gastroenterology,
E L Blair, and
E R Grund, and
J D Reed, and
D J Sanders, and
M H Thompson, and
C W Venables
January 1987,
European journal of clinical pharmacology,
E L Blair, and
E R Grund, and
J D Reed, and
D J Sanders, and
M H Thompson, and
C W Venables
January 1984,
Scandinavian journal of gastroenterology,
E L Blair, and
E R Grund, and
J D Reed, and
D J Sanders, and
M H Thompson, and
C W Venables
January 1976,
Arzneimittel-Forschung,
E L Blair, and
E R Grund, and
J D Reed, and
D J Sanders, and
M H Thompson, and
C W Venables
January 1974,
Scandinavian journal of gastroenterology,
E L Blair, and
E R Grund, and
J D Reed, and
D J Sanders, and
M H Thompson, and
C W Venables
February 1986,
Digestive diseases and sciences,
E L Blair, and
E R Grund, and
J D Reed, and
D J Sanders, and
M H Thompson, and
C W Venables
January 1970,
Surgical forum,
E L Blair, and
E R Grund, and
J D Reed, and
D J Sanders, and
M H Thompson, and
C W Venables
January 1985,
Terapevticheskii arkhiv,
E L Blair, and
E R Grund, and
J D Reed, and
D J Sanders, and
M H Thompson, and
C W Venables
September 1983,
The Journal of the Association of Physicians of India,
