Biomaterial Database

Genetic structure of local populations of Lutzomyia longipalpis (Diptera: Psychodidae) in central Colombia. 1998

L E Munstermann, and A C Morrison, and C Ferro, and R Pardo, and M Torres

Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520-8034, USA.

Lutzomyia longipalpis (Lutz & Neiva), the sand fly vector of American visceral leishmaniasis in the New World tropics, has a broad but discontinuous geographical distribution from southern Mexico to Argentina. A baseline for population genetic structure and genetic variability for this species was obtained by analyzing 5 local, peridomestic populations at the approximate center of its distribution, the Magdalena River Valley of central Colombia. Three populations of L. longipalpis from El Callejón, a small rural community, were compared with 2 populations from neighboring areas 12 and 25 km distant for genetic variation at 15 isoenzyme loci. The mean heterozygosity ranged from 11 to 16%, with 1.2 to 2.3 alleles detected per locus. Nei's genetic distances among the populations were very low, ranging from 0.001 to 0.007. Gene flow estimates based on FST indicated high levels of gene flow among local L. longipalpis populations, with minimal population substructuring.

UI	MeSH Term	Description	Entries
D011110	Polymorphism, Genetic	The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.	Gene Polymorphism,Genetic Polymorphism,Polymorphism (Genetics),Genetic Polymorphisms,Gene Polymorphisms,Polymorphism, Gene,Polymorphisms (Genetics),Polymorphisms, Gene,Polymorphisms, Genetic
D011153	Population	The total number of individuals inhabiting a particular region or area.	School Age Population,School-Age Population,Population, School Age,Population, School-Age,Populations,Populations, School Age,Populations, School-Age,School Age Populations,School-Age Populations
D011576	Psychodidae	Small, hairy, moth-like flies which are of considerable public health importance as vectors of certain pathogenic organisms. Important disease-related genera are PHLEBOTOMUS, Lutzomyia, and Sergentomyia.	Lutzomyia,Moth Flies,Phlebotominae,Psychodinae,Sandflies,Sergentomyia,Sand Flies,Flies, Moth,Flies, Sand,Fly, Moth,Fly, Sand,Lutzomyias,Moth Fly,Sand Fly,Sandfly,Sergentomyias
D003105	Colombia	A country in northern South America, bordering the Caribbean Sea, between Panama and Venezuela, and bordering the north Pacific Ocean, between Ecuador and Panama. The capital is Bogota.
D000483	Alleles	Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.	Allelomorphs,Allele,Allelomorph
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia