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Thirteen schizophrenic patients who developed abnormal psychotic behavior as an adverse reaction to a neuroleptic are described. A. Three patients showed a marked increase in the psychopathology during neuroleptic treatment. These episodes were treated by decreasing or discontinuing the neuroleptics. They did not respond to anticholinergic durgs nor did they respond to an increase in dosage, (another side effect previously reported and referred to here) indeed this treatment worsened the situation. B. Ten patients showed a mixed picture of catatonic excitement or inhibition on neuroleptics and several developed hallucinatory episodes. All of these exacerbations were terminated by anticholinergic injections. Other more familiar CNS abnormalities produced by neuroleptics are briefly discussed.
G M Simpson, and
E Varga, and
J Haher
February 1991,
Journal of clinical psychopharmacology,
G M Simpson, and
E Varga, and
J Haher
August 1987,
The American journal of psychiatry,
G M Simpson, and
E Varga, and
J Haher
March 1984,
La Revue du praticien,
G M Simpson, and
E Varga, and
J Haher
April 2002,
Annales francaises d'anesthesie et de reanimation,
G M Simpson, and
E Varga, and
J Haher
December 1988,
Journal of clinical psychopharmacology,
G M Simpson, and
E Varga, and
J Haher
October 1984,
Medicina clinica,
G M Simpson, and
E Varga, and
J Haher
January 1976,
Annales de l'anesthesiologie francaise,
G M Simpson, and
E Varga, and
J Haher
January 1979,
Annales medico-psychologiques,
G M Simpson, and
E Varga, and
J Haher
July 1966,
Neurologia, neurochirurgia i psychiatria polska,
G M Simpson, and
E Varga, and
J Haher
January 2001,
Neuropsychiatry, neuropsychology, and behavioral neurology,
