Biomaterial Database

Cat retinal ganglion cells projecting to the superior colliculus as shown by the horseradish peroxidase method. 1976

H H Magalhães-Castro, and L A Murata, and B Magalhães-Castro

1. Cat retinal ganglion cells projecting to the superior colliculus (SC) were detected in flat whole-mounts of Nissl-stained retinas by means of unilateral intracollicular injections of horseradish peroxidase (HRP). 2. With the purpose of drawing a comparison between HRP-labeled ganglion cells and the remaining population of unlabeled ganglion cells, the latter were classified according to their perikaryal characteristics into three groups: large, medium and small ganglion cells. Measurements of perikaryal sizes of ganglion cells distributed from the central area to the periphery of the retina showed that large cells ranged from 20 to 44 mum, medium cells from 15 to 30 mum and small cells from 8 to 17 mum. 3. Peroxidase-labeled retinal ganglion cells (HRP-cells) occurred among representatives of each of the three groups into which retinal ganglion cells had been classified. Small HRP-cells clearly constituted the majority of the HRP-cell population. When the injection site was restricted to the superior colliculus, medium HRP-cells as large as 19 mum were only occasionally observed, the 15 to 18 mum range being predominant over the medium cell population. 4. Medium HRP-cells larger than 20 mum were a common finding only when the injection site involved the pretectal nuclei and were never observed when the injection site was restricted to superior colliculus. 5. Possibility of a correspondence between the large, medium and small HRP-cells of the present study with, respectively, the physiological types Y-, X- and W- of cat retinal ganglion cells is discussed.

UI	MeSH Term	Description	Entries
D012160	Retina	The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.	Ora Serrata
D002415	Cats	The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)	Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D002452	Cell Count	The number of CELLS of a specific kind, usually measured per unit volume or area of sample.	Cell Density,Cell Number,Cell Counts,Cell Densities,Cell Numbers,Count, Cell,Counts, Cell,Densities, Cell,Density, Cell,Number, Cell,Numbers, Cell
D006735	Horseradish Peroxidase	An enzyme isolated from horseradish which is able to act as an antigen. It is frequently used as a histochemical tracer for light and electron microscopy. Its antigenicity has permitted its use as a combined antigen and marker in experimental immunology.	Alpha-Peroxidase,Ferrihorseradish Peroxidase,Horseradish Peroxidase II,Horseradish Peroxidase III,Alpha Peroxidase,II, Horseradish Peroxidase,III, Horseradish Peroxidase,Peroxidase II, Horseradish,Peroxidase III, Horseradish,Peroxidase, Ferrihorseradish,Peroxidase, Horseradish
D000344	Afferent Pathways	Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.	Afferent Pathway,Pathway, Afferent,Pathways, Afferent
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013477	Superior Colliculi	The anterior pair of the quadrigeminal bodies which coordinate the general behavioral orienting responses to visual stimuli, such as whole-body turning, and reaching.	Colliculus, Superior,Optic Lobe, Human,Optic Lobe, Mammalian,Optic Tectum,Anterior Colliculus,Superior Colliculus,Tectum, Optic,Colliculi, Superior,Colliculus, Anterior,Human Optic Lobe,Human Optic Lobes,Mammalian Optic Lobe,Mammalian Optic Lobes,Optic Lobes, Human,Optic Lobes, Mammalian,Optic Tectums,Tectums, Optic