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Immunoglobulins in serum and proximal intestinal fluids and secretion of IgA by cultured jejunal mucosa were measured in 12 healthy subjects and 36 patients with Crohn's disease. Concentrations of IgA, IgG, IgM, and IgE in serum and intestinal fluids were similar in the two groups, except for increased serum IgA concentrations in the patients. Elevation of IgA and chronicity of disease were correlated, which suggests that the IgA alteration was a response to duration of disease rather than a primary pathogenetic factor. IgA secretion by cultured jejunum was similar in control and patient groups. Thus, no evidence was found that abnormalities of secretory immunoglobulins are pathogenetically involved in Crohn's disease.
E G Jones, and
W L Beeken, and
K D Roessner, and
W R Brown
August 1988,
Journal of clinical gastroenterology,
E G Jones, and
W L Beeken, and
K D Roessner, and
W R Brown
September 1974,
The American journal of digestive diseases,
E G Jones, and
W L Beeken, and
K D Roessner, and
W R Brown
January 1992,
Digestive diseases and sciences,
E G Jones, and
W L Beeken, and
K D Roessner, and
W R Brown
May 1974,
Gut,
E G Jones, and
W L Beeken, and
K D Roessner, and
W R Brown
March 1975,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
E G Jones, and
W L Beeken, and
K D Roessner, and
W R Brown
April 1990,
Gastroenterology,
E G Jones, and
W L Beeken, and
K D Roessner, and
W R Brown
March 1973,
Clinical and experimental immunology,
E G Jones, and
W L Beeken, and
K D Roessner, and
W R Brown
January 1977,
Scandinavian journal of gastroenterology,
E G Jones, and
W L Beeken, and
K D Roessner, and
W R Brown
January 1974,
International archives of allergy and applied immunology,
E G Jones, and
W L Beeken, and
K D Roessner, and
W R Brown
January 1987,
Advances in experimental medicine and biology,
