-transparent.png){kind=logo}
We describe MR findings in patients with Minamata disease who have been followed for a long time. All patients examined were affected after daily eating of a large quantity of methylmercury-contaminated seafood, from 1955 to 1958, and showed typical neurological findings. On MR images, the visual cortex, the cerebellar vermis and hemispheres, and the postcentral cortex are significantly atrophic in Minamata disease. The visual cortex is slightly hypointense on T1-weighted images and hyperintense on T2-weighted images, probably representing the pathologic changes of status spongiosus. MRI can demonstrate the lesions located in the calcarine area, cerebellum, and postcentral gyri, which are probably related to three of the characteristic manifestations of this disease: the constriction of the visual fields, ataxia, and sensory disturbance, respectively.
Y Korogi, and
M Takahashi, and
T Okajima, and
K Eto
August 1970,
Kangogaku zasshi,
Y Korogi, and
M Takahashi, and
T Okajima, and
K Eto
February 1975,
Rinsho byori. The Japanese journal of clinical pathology,
Y Korogi, and
M Takahashi, and
T Okajima, and
K Eto
December 1982,
Neurology,
Y Korogi, and
M Takahashi, and
T Okajima, and
K Eto
July 1975,
Journal of the American Medical Women's Association (1972),
Y Korogi, and
M Takahashi, and
T Okajima, and
K Eto
August 1995,
Internal medicine (Tokyo, Japan),
Y Korogi, and
M Takahashi, and
T Okajima, and
K Eto
May 1969,
Nihon Ishikai zasshi. Journal of the Japan Medical Association,
Y Korogi, and
M Takahashi, and
T Okajima, and
K Eto
October 1973,
Nippon Ganka Gakkai zasshi,
Y Korogi, and
M Takahashi, and
T Okajima, and
K Eto
March 1984,
Rinsho shinkeigaku = Clinical neurology,
Y Korogi, and
M Takahashi, and
T Okajima, and
K Eto
September 1995,
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes,
Y Korogi, and
M Takahashi, and
T Okajima, and
K Eto
August 1972,
Nippon Ganka Gakkai zasshi,
