Triiodothyronine (T3) and thyroxine (T4) levels in Rana curtipes during development and metamorphosis. 1997

T T Valamparampil, and O V Oommen
Post-Graduate Department of Zoology, St. Berchmans' College, Changanacherry, India.

During premetamorphosis, levels of circulating triiodothyronine (T3) and thyroxine (T4) were below the limits of detection of RIA. They became detectable in late prometamorphic stages. A gradual increase in T3 and T4 was observed during this period. A sharp rise in hormone levels was apparent at the onset of metamorphic climax. Peak levels of both hormones were found at Taylor-Kollros stage XXI. The T3 reached a peak level of 101.4 ng/dl, about 3 fold increase over the level at prometamorphosis. Thereafter the circulating hormones (particularly T4) decreased rapidly and reached levels similar to prometamorphic stages. Significant high levels of thyroid hormones (T3 and T4) in metamorphic climax suggest that like other anurans, elevation of these hormones is required for normal metamorphosis in R. curtipes tadpoles.

UI MeSH Term Description Entries
D008675 Metamorphosis, Biological Profound physical changes during maturation of living organisms from the immature forms to the adult forms, such as from TADPOLES to frogs; caterpillars to BUTTERFLIES. Biological Metamorphosis,Biological Metamorphoses,Metamorphoses, Biological
D011898 Ranidae The family of true frogs of the order Anura. The family occurs worldwide except in Antarctica. Frogs, True,Rana,Frog, True,True Frog,True Frogs
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013974 Thyroxine The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. L-Thyroxine,Levothyroxine,T4 Thyroid Hormone,3,5,3',5'-Tetraiodothyronine,Berlthyrox,Dexnon,Eferox,Eltroxin,Eltroxine,Euthyrox,Eutirox,L-3,5,3',5'-Tetraiodothyronine,L-Thyrox,L-Thyroxin Henning,L-Thyroxin beta,L-Thyroxine Roche,Levo-T,Levothroid,Levothyroid,Levothyroxin Deladande,Levothyroxin Delalande,Levothyroxine Sodium,Levoxine,Levoxyl,Lévothyrox,Novothyral,Novothyrox,O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine,O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine,Oroxine,Sodium Levothyroxine,Synthroid,Synthrox,Thevier,Thyrax,Thyroxin,Tiroidine,Tiroxina Leo,Unithroid,L Thyrox,L Thyroxin Henning,L Thyroxin beta,L Thyroxine,L Thyroxine Roche,Levo T,Thyroid Hormone, T4
D014284 Triiodothyronine A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3. Liothyronine,T3 Thyroid Hormone,3,3',5-Triiodothyronine,Cytomel,Liothyronine Sodium,Thyroid Hormone, T3

Related Publications

T T Valamparampil, and O V Oommen
May 1974, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
T T Valamparampil, and O V Oommen
January 1989, Wiadomosci lekarskie (Warsaw, Poland : 1960),
T T Valamparampil, and O V Oommen
July 1988, Laboratory animals,
T T Valamparampil, and O V Oommen
December 1972, Mayo Clinic proceedings,
T T Valamparampil, and O V Oommen
July 1979, Danish medical bulletin,
T T Valamparampil, and O V Oommen
November 1976, The Indian journal of medical research,
Copied contents to your clipboard!