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The circadian periodicity of urinary 17-ketogenic steroids (17-KGS), 17-ketosteroids (17-KS) and creatinine (Cr) was studied preoperatively and on the 9th postoperative day in 25 histopathologically proved breast cancer patients and in 15 healthy Indian women under tropical conditions. A statistically significant rhythm was observed in healthy participants for all three variables. Urinary corticoids were markedly elevated in breast cancer patients irrespective of the stage of the disease in comparison with healthy controls. The degree of elevation was more pronounced preoperatively in advanced stage breast cancer in comparison with other groups. After mastectomy, the values of all three variables declined markedly, approaching usual values with a circadian rhythm resembling the pattern found in clinical health.
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A A Mahdi, and
S Misra, and
S P Rai, and
D Singh, and
G Cornélissen, and
F Halberg
January 1956,
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R Singh, and
R K Singh, and
A A Mahdi, and
S Misra, and
S P Rai, and
D Singh, and
G Cornélissen, and
F Halberg
July 1980,
The American journal of physiology,
R Singh, and
R K Singh, and
A A Mahdi, and
S Misra, and
S P Rai, and
D Singh, and
G Cornélissen, and
F Halberg
May 1965,
Die Naturwissenschaften,
R Singh, and
R K Singh, and
A A Mahdi, and
S Misra, and
S P Rai, and
D Singh, and
G Cornélissen, and
F Halberg
September 2013,
Biostatistics (Oxford, England),
R Singh, and
R K Singh, and
A A Mahdi, and
S Misra, and
S P Rai, and
D Singh, and
G Cornélissen, and
F Halberg
November 1976,
The Journal of clinical endocrinology and metabolism,
R Singh, and
R K Singh, and
A A Mahdi, and
S Misra, and
S P Rai, and
D Singh, and
G Cornélissen, and
F Halberg
October 1976,
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R Singh, and
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A A Mahdi, and
S Misra, and
S P Rai, and
D Singh, and
G Cornélissen, and
F Halberg
June 1990,
The Journal of tropical medicine and hygiene,
R Singh, and
R K Singh, and
A A Mahdi, and
S Misra, and
S P Rai, and
D Singh, and
G Cornélissen, and
F Halberg
January 1981,
Physiology & behavior,
R Singh, and
R K Singh, and
A A Mahdi, and
S Misra, and
S P Rai, and
D Singh, and
G Cornélissen, and
F Halberg
September 1974,
Chronobiologia,
R Singh, and
R K Singh, and
A A Mahdi, and
S Misra, and
S P Rai, and
D Singh, and
G Cornélissen, and
F Halberg
October 1970,
Die Naturwissenschaften,
