Biological, rather then purely technical approach seems to be very essential to ensure better results in alloplasty of the cornea. The diseased corneal tissue (especially, after corneal burns) usually fails to accept a keratoprosthesis permanently. The cornea must, therefore, be biologically reconstructed by transplantation of autogenous tissue. Autogenous fascia lata, periosteum, sclera and auricular cartilage have been tried in the present work to surve the purpose. Autogenous sclera and cartilage proved to be best materials, the latter having an important advantage of being easily obtainable. Experimental studies (including hystological control) proved the method of "Chondrokeratoplasty" to be well founded. During the past four years the method has been used on the eyes of 18 patients with most severe corneal lesions unmanageable by the usual graft technique. The Keratoprosthesis must be buried under the cartilage disk until the adequate nutrition is developed and full vitality of the graft is achieved. Only then the cartilage disk is trephined in its centre and the optical part of the keratoprosthesis is exposed. Technically, the procedure is much simpler as compared to the procedure of odonto-keratoprosthesis by strampelly. The results seem to be highly encouraging. So far there was no extrusion after chondrokeratoprosthesis procedure.