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We report the case of a 36-year-old, previously healthy male patient presenting with progressive shortness of breath and dry cough. Chest X-ray revealed a diffuse micronodular interstitial pattern and pulmonary function tests showed reduced diffusion capacity, a restrictive pattern and obstructive airflow limitation. Transbronchial biopsy disclosed lymphangiosis carcinomatosa. The primary tumor was adenocarcinoma of the stomach. Differential diagnosis and the diagnostic approach to interstitial lung diseases are discussed. History, clinical findings, radiological and functional tests, as well as blood chemistry, serve to narrow down the differential diagnosis. The main further investigative steps are bronchoscopy with broncho-alveolar lavage and transbronchial biopsies, high resolution computer tomography, and thoracoscopic biopsy.
R Siebenschein, and
P Ackle, and
G Singer
October 1959,
Schweizerische medizinische Wochenschrift,
R Siebenschein, and
P Ackle, and
G Singer
March 2005,
The Pediatric infectious disease journal,
R Siebenschein, and
P Ackle, and
G Singer
February 1989,
Deutsche medizinische Wochenschrift (1946),
R Siebenschein, and
P Ackle, and
G Singer
January 1967,
Tuberkuloza,
R Siebenschein, and
P Ackle, and
G Singer
January 2011,
Duodecim; laaketieteellinen aikakauskirja,
R Siebenschein, and
P Ackle, and
G Singer
January 2017,
Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia,
R Siebenschein, and
P Ackle, and
G Singer
November 1988,
Chest,
R Siebenschein, and
P Ackle, and
G Singer
October 1984,
JAMA,
R Siebenschein, and
P Ackle, and
G Singer
January 1999,
Klinicheskaia meditsina,
R Siebenschein, and
P Ackle, and
G Singer
October 1998,
Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society,
