Regional tongue sensitivity for sweetness and pungency of ethanol-aspartame mixtures. 1998

A M Calviño
Cátedra de Fisiología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.

Binary mixtures of aspartame prepared at three levels of concentration and dissolved in four ethanolic dilutions were perceptually evaluated. Sweet-pungent combinations were presented in solution or in disks of filter paper (paper) soaked in the solutions. Variations in sweetness and pungency were examined at two oral loci including the tip and the back plus the front of the tongue in the liquid condition or the tip and the back of the tongue in the paper condition. A similar behavior was observed in liquid and paper conditions; as the concentration of aspartame and ethanol increased so did the intensity for sweet and pungent qualities. Whereas sweetness was not influenced by ethanol addition (2-8% V/V), a suppressive effect of aspartame (1-4 mM) on pungency was noted for liquid but not for the paper condition. Sweetness was enhanced when the back plus the front of the tongue was stimulated by solutions. Finally, there was a complex pattern of regional effects on the perceived pungency of alcoholic-sweet solutions that was not replicated in the paper condition.

UI MeSH Term Description Entries
D008297 Male Males
D010209 Paper Thin sheets made from wood pulp and other fibrous substances, used for writing, drawing, printing, image duplication or wrapping. Papers
D004305 Dose-Response Relationship, Drug The relationship between the dose of an administered drug and the response of the organism to the drug. Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000431 Ethanol A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES. Alcohol, Ethyl,Absolute Alcohol,Grain Alcohol,Alcohol, Absolute,Alcohol, Grain,Ethyl Alcohol
D001218 Aspartame Flavoring agent sweeter than sugar, metabolized as PHENYLALANINE and ASPARTIC ACID. Aspartylphenylalanine Methyl Ester,Canderel,Goldswite,Hermesetas Gold,Methyl Aspartylphenylalanine,Milisucre,Nozucar,NutraSweet,SC-18862,Tri-Sweet,Aspartylphenylalanine, Methyl,Gold, Hermesetas,Methyl Ester, Aspartylphenylalanine,SC 18862,SC18862,Tri Sweet,TriSweet
D012996 Solutions The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed) Solution
D013649 Taste The ability to detect chemicals through gustatory receptors in the mouth, including those on the TONGUE; the PALATE; the PHARYNX; and the EPIGLOTTIS. Gustation,Taste Sense,Gustations,Sense, Taste,Senses, Taste,Taste Senses,Tastes
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