Accuracy of stereotactic core-needle breast biopsy in atypical ductal hyperplasia. 1998

P H Lin, and J C Clyde, and D M Bates, and J M Garcia, and G H Matsumoto, and G W Girvin
Spokane Surgical Group, Washington, USA.

BACKGROUND The histologic diagnosis of atypical ductal hyperplasia (ADH) has been reported as having a high rate of malignancy, either ductal carcinoma in situ (DCIS) or invasive ductal carcinoma (IDC). We reviewed our surgical group's experience with stereotactic core-needle biopsies (SCNB), specifically looking at the follow-up of ADH. METHODS From November 1994 through July 1997 our group performed 539 SCNB. Twenty-one patients (4%) were diagnosed as ADH. Eighteen patients had subsequent wire-localized excisional biopsies. Three patients were followed up mammographically. One patient refused follow-up. RESULTS Of the 18 patients who underwent excisional biopsies, 2 patients were found to have DCIS and 1 patient had lobular carcinoma in-situ. There were no cases of IDC. CONCLUSIONS Our results show a much lower incidence of malignancy in cases of ADH found on SCNB than has been previously reported. While the standard of care is still to follow up ADH found on SCNB with excisional biopsy, more data may justify following up certain subsets of patients.

UI MeSH Term Description Entries
D006965 Hyperplasia An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells. Hyperplasias
D001940 Breast In humans, one of the paired regions in the anterior portion of the THORAX. The breasts consist of the MAMMARY GLANDS, the SKIN, the MUSCLES, the ADIPOSE TISSUE, and the CONNECTIVE TISSUES. Breasts
D001941 Breast Diseases Pathological processes of the BREAST. Endocrine Breast Diseases,Breast Disease,Breast Disease, Endocrine,Breast Diseases, Endocrine,Disease, Breast,Disease, Endocrine Breast,Diseases, Breast,Diseases, Endocrine Breast,Endocrine Breast Disease
D001943 Breast Neoplasms Tumors or cancer of the human BREAST. Breast Cancer,Breast Tumors,Cancer of Breast,Breast Carcinoma,Cancer of the Breast,Human Mammary Carcinoma,Malignant Neoplasm of Breast,Malignant Tumor of Breast,Mammary Cancer,Mammary Carcinoma, Human,Mammary Neoplasm, Human,Mammary Neoplasms, Human,Neoplasms, Breast,Tumors, Breast,Breast Carcinomas,Breast Malignant Neoplasm,Breast Malignant Neoplasms,Breast Malignant Tumor,Breast Malignant Tumors,Breast Neoplasm,Breast Tumor,Cancer, Breast,Cancer, Mammary,Cancers, Mammary,Carcinoma, Breast,Carcinoma, Human Mammary,Carcinomas, Breast,Carcinomas, Human Mammary,Human Mammary Carcinomas,Human Mammary Neoplasm,Human Mammary Neoplasms,Mammary Cancers,Mammary Carcinomas, Human,Neoplasm, Breast,Neoplasm, Human Mammary,Neoplasms, Human Mammary,Tumor, Breast
D002114 Calcinosis Pathologic deposition of calcium salts in tissues. Calcification, Pathologic,Calcinosis, Tumoral,Microcalcification,Microcalcinosis,Pathologic Calcification,Calcinoses,Calcinoses, Tumoral,Microcalcifications,Microcalcinoses,Tumoral Calcinoses,Tumoral Calcinosis
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001707 Biopsy, Needle Removal and examination of tissue obtained through a transdermal needle inserted into the specific region, organ, or tissue being analyzed. Aspiration Biopsy,Puncture Biopsy,Aspiration Biopsies,Biopsies, Aspiration,Biopsies, Needle,Biopsies, Puncture,Biopsy, Aspiration,Biopsy, Puncture,Needle Biopsies,Needle Biopsy,Puncture Biopsies
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity

Related Publications

P H Lin, and J C Clyde, and D M Bates, and J M Garcia, and G H Matsumoto, and G W Girvin
June 1997, Annals of surgical oncology,
P H Lin, and J C Clyde, and D M Bates, and J M Garcia, and G H Matsumoto, and G W Girvin
May 1996, AJR. American journal of roentgenology,
P H Lin, and J C Clyde, and D M Bates, and J M Garcia, and G H Matsumoto, and G W Girvin
January 2008, Journal de radiologie,
P H Lin, and J C Clyde, and D M Bates, and J M Garcia, and G H Matsumoto, and G W Girvin
June 2003, Archives of surgery (Chicago, Ill. : 1960),
P H Lin, and J C Clyde, and D M Bates, and J M Garcia, and G H Matsumoto, and G W Girvin
March 1998, Journal of surgical oncology,
P H Lin, and J C Clyde, and D M Bates, and J M Garcia, and G H Matsumoto, and G W Girvin
January 2001, The breast journal,
P H Lin, and J C Clyde, and D M Bates, and J M Garcia, and G H Matsumoto, and G W Girvin
October 2012, Ultraschall in der Medizin (Stuttgart, Germany : 1980),
P H Lin, and J C Clyde, and D M Bates, and J M Garcia, and G H Matsumoto, and G W Girvin
March 1997, Radiology,
P H Lin, and J C Clyde, and D M Bates, and J M Garcia, and G H Matsumoto, and G W Girvin
October 2009, World journal of surgical oncology,
P H Lin, and J C Clyde, and D M Bates, and J M Garcia, and G H Matsumoto, and G W Girvin
April 2009, AJR. American journal of roentgenology,
Copied contents to your clipboard!