Organochlorine pesticides, polychlorinated biphenyls and dioxins in human milk from Swedish mothers. 1998

S S Atuma, and L Hansson, and H Johnsson, and S Slorach, and C A de Wit, and G Lindstrom
National Food Administration, Uppsala, Sweden.

Ten human milk samples, collected from two towns, Uppsala and Sundsvall, in Sweden in 1994 were analysed for selected chlorinated pesticides (HCB, alpha- and gamma-HCH, DDT, DDD and DDE) and PCB congeners (PCBs 28, 77, 101, 105, 118, 126, 138, 153, 156, 158, 167, 169 and 180), PCDDs and PCDFs. The levels found in this study, including the toxic equivalent (TEQ) values, showed a slight downward trend between 1986 and 1994 and are somewhat lower than levels reported from other countries. The contribution of both the mono- and non-ortho PCBs, together with that of PCDD/Fs to the total TEQ values was assessed. Over 70% of the TCDD equivalents was derived from PCBs, PCB 126 being the major contributor. Other high PCB contributors were PCBs 156 and 118. The levels of HCB, alpha- and gamma-HCH, and sigma DDT were generally higher in Uppsala than in Sundsvall. They were, however, over 50% lower in 1990 than in 1986 and have since changed little. For the PCDD/Fs the results show a marked decrease (ca 50%) in levels between 1986 and 1994. There is an indication that PCB 153 and PCB 126 may be good indicators for total PCB and TEQ levels respectively.

UI MeSH Term Description Entries
D007306 Insecticides Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics. Insecticide
D008895 Milk, Human Milk that is produced by HUMAN MAMMARY GLANDS. Breast Milk,Human Milk,Milk, Breast
D011078 Polychlorinated Biphenyls Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants. PCBs,Polychlorinated Biphenyl,Polychlorobiphenyl Compounds,Biphenyl, Polychlorinated,Biphenyls, Polychlorinated,Compounds, Polychlorobiphenyl
D011786 Quality Control A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed) Control, Quality,Controls, Quality,Quality Controls
D004147 Dioxins A family of compounds that contain the 1,4-dioxin structure. Many specific dioxin derivatives are listed as CARCINOGENS; TERATOGENS; or MUTAGENS. Dioxin
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013548 Sweden Country in northern Europe, bordering the Baltic Sea, between Finland and Norway. The capital is Stockholm.

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