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Rod-only electroretinograms (ERGs) were recorded from 6-week and 4-month-old normal human infants. The leading edge of the rod a-wave was fitted with a model of the activation phase of phototransduction to provide estimates of S (a sensitivity parameter) and RmP3 (the maximum saturated photoreceptor response) at each of the investigated ages. Both S and RmP3 increased over the first postnatal months but followed different developmental time courses with S approaching adult-like values sooner than RmP3. The changes in S and RmP3 can be interpreted within the context of a model incorporating the combined effects of increased levels of rhodopsin and the changing structure of the rod outer segment during development.
S Nusinowitz, and
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December 1988,
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January 1987,
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The Journal of the Dental Association of Thailand,
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Infancy : the official journal of the International Society on Infant Studies,
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Vision research,
S Nusinowitz, and
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S Nusinowitz, and
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Developmental psychobiology,
