[The morphological changes in the internal organs in hemochromatosis]. 1998

Iu I Pigolkin, and T K Osipenkova

Visceral changes were studied by histological and electron-microscopic methods in cadavers of 18 subjects dead from hemochromatosis. Pronounced visceral changes in all cases represented a characteristic tetrad of signs: bronze-colored skin, pigmentary cirrhosis of the liver, involvement of the pancreas, and cardiomyopathy. In forensic medical practice hemochromatosis can be found in subjects who were probably genetically predisposed to it and, as a rule, had a history of alcohol abuse. Among the numerous complications of the disease, the most incident are cardiac pathology (dilatation cardiomyopathy) and diabetes mellitus with concomitant intoxications caused by various inflammations.

UI MeSH Term Description Entries
D008297 Male Males
D008854 Microscopy, Electron Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen. Electron Microscopy
D002423 Cause of Death Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint. Causes of Death,Death Cause,Death Causes
D005260 Female Females
D006333 Heart Failure A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. Cardiac Failure,Heart Decompensation,Congestive Heart Failure,Heart Failure, Congestive,Heart Failure, Left-Sided,Heart Failure, Right-Sided,Left-Sided Heart Failure,Myocardial Failure,Right-Sided Heart Failure,Decompensation, Heart,Heart Failure, Left Sided,Heart Failure, Right Sided,Left Sided Heart Failure,Right Sided Heart Failure
D006432 Hemochromatosis A disorder of iron metabolism characterized by a triad of HEMOSIDEROSIS; LIVER CIRRHOSIS; and DIABETES MELLITUS. It is caused by massive iron deposits in parenchymal cells that may develop after a prolonged increase of iron absorption. (Jablonski's Dictionary of Syndromes & Eponymic Diseases, 2d ed) Diabetes, Bronze,Bronze Diabetes,Bronzed Cirrhosis,Familial Hemochromatosis,Genetic Hemochromatosis,Haemochromatosis,Hemochromatoses,Iron Storage Disorder,Pigmentary Cirrhosis,Primary Hemochromatosis,Troisier-Hanot-Chauffard Syndrome,Von Recklenhausen-Applebaum Disease,Bronzed Cirrhoses,Cirrhoses, Bronzed,Cirrhoses, Pigmentary,Cirrhosis, Bronzed,Cirrhosis, Pigmentary,Disease, Von Recklenhausen-Applebaum,Diseases, Von Recklenhausen-Applebaum,Disorder, Iron Storage,Disorders, Iron Storage,Familial Hemochromatoses,Genetic Hemochromatoses,Haemochromatoses,Hemochromatose,Hemochromatoses, Familial,Hemochromatoses, Genetic,Hemochromatosis, Familial,Hemochromatosis, Genetic,Iron Storage Disorders,Pigmentary Cirrhoses,Recklenhausen-Applebaum Disease, Von,Recklenhausen-Applebaum Diseases, Von,Storage Disorder, Iron,Storage Disorders, Iron,Syndrome, Troisier-Hanot-Chauffard,Syndromes, Troisier-Hanot-Chauffard,Troisier Hanot Chauffard Syndrome,Troisier-Hanot-Chauffard Syndromes,Von Recklenhausen Applebaum Disease,Von Recklenhausen-Applebaum Diseases
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001344 Autopsy Postmortem examination of the body. Autopsies,Post-Mortem Examination,Postmortem Examination,Examination, Post-Mortem,Examination, Postmortem,Examinations, Post-Mortem,Examinations, Postmortem,Post Mortem Examination,Post-Mortem Examinations,Postmortem Examinations
D014781 Viscera Any of the large interior organs in any one of the three great cavities of the body, especially in the abdomen.

Related Publications

Iu I Pigolkin, and T K Osipenkova
January 1956, Eksperimental'naia khirurgiia,
Iu I Pigolkin, and T K Osipenkova
January 2002, Arkhiv patologii,
Iu I Pigolkin, and T K Osipenkova
September 1975, Biulleten' eksperimental'noi biologii i meditsiny,
Iu I Pigolkin, and T K Osipenkova
January 1987, Arkhiv patologii,
Iu I Pigolkin, and T K Osipenkova
October 1977, Voenno-meditsinskii zhurnal,
Iu I Pigolkin, and T K Osipenkova
January 1966, Arkhiv patologii,
Iu I Pigolkin, and T K Osipenkova
January 1962, Arkhiv patologii,
Iu I Pigolkin, and T K Osipenkova
January 1974, Patologia polska,
Iu I Pigolkin, and T K Osipenkova
January 1988, Voenno-meditsinskii zhurnal,
Copied contents to your clipboard!