Biomaterial Database

Analysis of respiratory mechanics during artificial ventilation. 1998

J Guttmann

Anaesthesiologische Universitätsklinik, Albert-Ludwigs-Universität Freiburg.

Mechanical or artificial ventilation is the most important life-saving therapeutic instrument in modern intensive care medicine. The ventilator takes on the convective transport of the respiratory gas, i.e. delivery of oxygen and removal of carbon dioxide. The technical gas delivery system (ventilator, respiratory tubing system, gas humidifier) and the respiratory system (lungs and thorax) of the patients form a connected pneumatic system of high complexity. The respiratory system produces a mechanical impedance to ventilator output. Impedance is composed of an elastic, a non-elastic, i.e. resistive, and an inertive part. The corresponding indices describing respiratory mechanics are compliance, flow resistance and inertance. Based on the equation of motion of the respiratory system, several methods of analysing respiratory mechanics during mechanical ventilation are described. Quantitative analysis of respiratory system mechanics (a) is a prerequisite for the understanding of the complex patient-ventilator interaction, (b) provides important clinical information on pulmonary function and the course of disease, and (c) allows the physician at the bedside to adjust the ventilatory settings to the needs of the individual patient.

UI	MeSH Term	Description	Entries
D008176	Lung Volume Measurements	Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle.	Lung Capacities,Lung Volumes,Capacity, Lung,Lung Capacity,Lung Volume,Lung Volume Measurement,Measurement, Lung Volume,Volume, Lung
D008432	Mathematical Computing	Computer-assisted interpretation and analysis of various mathematical functions related to a particular problem.	Statistical Computing,Computing, Statistical,Mathematic Computing,Statistical Programs, Computer Based,Computing, Mathematic,Computing, Mathematical,Computings, Mathematic,Computings, Mathematical,Computings, Statistical,Mathematic Computings,Mathematical Computings,Statistical Computings
D012121	Respiration, Artificial	Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have RESPIRATORY INSUFFICIENCY to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2).	Ventilation, Mechanical,Mechanical Ventilation,Artificial Respiration,Artificial Respirations,Mechanical Ventilations,Respirations, Artificial,Ventilations, Mechanical
D012122	Ventilators, Mechanical	Mechanical devices used to produce or assist pulmonary ventilation.	Mechanical Ventilator,Mechanical Ventilators,Respirators,Ventilators, Pulmonary,Pulmonary Ventilator,Pulmonary Ventilators,Ventilator, Pulmonary,Ventilators,Respirator,Ventilator,Ventilator, Mechanical
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001696	Biomechanical Phenomena	The properties, processes, and behavior of biological systems under the action of mechanical forces.	Biomechanics,Kinematics,Biomechanic Phenomena,Mechanobiological Phenomena,Biomechanic,Biomechanic Phenomenas,Phenomena, Biomechanic,Phenomena, Biomechanical,Phenomena, Mechanobiological,Phenomenas, Biomechanic
D015656	Respiratory Mechanics	The physical or mechanical action of the LUNGS; DIAPHRAGM; RIBS; and CHEST WALL during respiration. It includes airflow, lung volume, neural and reflex controls, mechanoreceptors, breathing patterns, etc.	Breathing Mechanics,Breathing Mechanic,Mechanic, Breathing,Mechanic, Respiratory,Mechanics, Breathing,Mechanics, Respiratory,Respiratory Mechanic