-transparent.png){kind=logo}
BACKGROUND Sleep deprivation (SD) exerts a beneficial effect on mood and sleep in about 60% of depressed patients usually followed by a relapse into depression after the recovery night. Short phases of sleepiness, especially naps in the early morning, may be responsible for this phenomenon. METHODS To evaluate the effect of short, even ultrashort phases of sleep-microsleep (MS) during partial sleep deprivation (PSD) on mood, cognitive psychomotor performance (CPP), and sleep, an electroencephalograph (EEG) was continuously recorded over 60 hours in 12 patients with major depression. Subjective mood was assessed by a visual analogue scale and CPP by a letter cancellation test. RESULTS The results illustrate that in depressed patients during PSD the amount of MS is increased, predominantly in the early morning, which was subjectively unrecognized and not observed by nursing staff. Patients with a low cumulative amount of MS during PSD improved significantly in mood, CPP, and sleep pattern compared to the patients with a high amount of MS who showed only slight changes. CONCLUSIONS Therefore, accumulated MS may influence the SD-induced positive effects in depressed patients.
U Hemmeter, and
R Bischof, and
M Hatzinger, and
E Seifritz, and
E Holsboer-Trachsler
October 2010,
Journal of psychiatric research,
U Hemmeter, and
R Bischof, and
M Hatzinger, and
E Seifritz, and
E Holsboer-Trachsler
November 2007,
Journal of psychiatric research,
U Hemmeter, and
R Bischof, and
M Hatzinger, and
E Seifritz, and
E Holsboer-Trachsler
March 1980,
Archives of general psychiatry,
U Hemmeter, and
R Bischof, and
M Hatzinger, and
E Seifritz, and
E Holsboer-Trachsler
January 1990,
Schweizer Archiv fur Neurologie und Psychiatrie (Zurich, Switzerland : 1985),
U Hemmeter, and
R Bischof, and
M Hatzinger, and
E Seifritz, and
E Holsboer-Trachsler
June 1992,
Journal of affective disorders,
U Hemmeter, and
R Bischof, and
M Hatzinger, and
E Seifritz, and
E Holsboer-Trachsler
April 2003,
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
U Hemmeter, and
R Bischof, and
M Hatzinger, and
E Seifritz, and
E Holsboer-Trachsler
February 1988,
Acta psychiatrica Scandinavica,
U Hemmeter, and
R Bischof, and
M Hatzinger, and
E Seifritz, and
E Holsboer-Trachsler
September 2003,
Journal of affective disorders,
U Hemmeter, and
R Bischof, and
M Hatzinger, and
E Seifritz, and
E Holsboer-Trachsler
January 1977,
Neuropsychobiology,
U Hemmeter, and
R Bischof, and
M Hatzinger, and
E Seifritz, and
E Holsboer-Trachsler
May 1990,
Psychiatrische Praxis,
