Biomaterial Database

[A case of pulmonary infiltration with eosinophilia caused by Ascaris suum]. 1998

W Matsuyama, and A Mizoguchi, and F Iwami, and M Kawabata, and M Osame

Department of Respiratory Medicine, Minami-kyushu National Hospital, Kagoshima, Japan.

A 46-year old man was admitted to our hospital with dry cough and diarrhea. His chest CT showed diffuse subpleural small nodular shadows. Eosinophilia and an increase of serum IgE were detected. Eosinophils were also increased in BALF. An antibody against Ascaris suum was positive in serum while other causes of eosinophilia (e. g., drugs, fungus, collagen disease) were absent. Ivermectin was administered and the diarrhea improved within 3 days. The abnormal chest shadows and dry cough disappeared 3 months later. Pulmonary infiltration with eosinophilia (PIE) syndrome caused by Ascaris suum was diagnosed because of the clinical course and serum examination results. Recently, zoonoses are increasing with the boom of oversea travel and "natural" foods. We report a case of PIE syndrome caused by Ascaris suum and describe the clinical features and the social significance including the origin of this disease.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011657	Pulmonary Eosinophilia	A condition characterized by infiltration of the lung with EOSINOPHILS due to inflammation or other disease processes. Major eosinophilic lung diseases are the eosinophilic pneumonias caused by infections, allergens, or toxic agents.	Eosinophilia, Pulmonary,Eosinophilic Pneumonia,Loeffler Syndrome,Pneumonia, Eosinophilic,Eosinophilias, Pulmonary,Pulmonary Eosinophilias,Simple Pulmonary Eosinophilia,Tropical Eosinophilic Pneumonia,Eosinophilic Pneumonia, Tropical,Eosinophilic Pneumonias,Eosinophilic Pneumonias, Tropical,Pneumonias, Eosinophilic,Pulmonary Eosinophilia, Simple,Simple Pulmonary Eosinophilias,Syndrome, Loeffler,Tropical Eosinophilic Pneumonias
D004797	Enzyme-Linked Immunosorbent Assay	An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.	ELISA,Assay, Enzyme-Linked Immunosorbent,Assays, Enzyme-Linked Immunosorbent,Enzyme Linked Immunosorbent Assay,Enzyme-Linked Immunosorbent Assays,Immunosorbent Assay, Enzyme-Linked,Immunosorbent Assays, Enzyme-Linked
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000909	Antibodies, Helminth	Immunoglobulins produced in a response to HELMINTH ANTIGENS.	Helminth Antibodies
D001196	Ascariasis	Infection by nematodes of the genus ASCARIS. Ingestion of infective eggs causes diarrhea and pneumonitis. Its distribution is more prevalent in areas of poor sanitation and where human feces are used for fertilizer.	Ascaris Infection,Ascariases,Ascaris Infections,Infection, Ascaris,Infections, Ascaris
D016266	Food Parasitology	The presence of parasites in food and food products. For the presence of bacteria, viruses, and fungi in food, FOOD MICROBIOLOGY is available.	Parasitology, Food
D017165	Ascaris suum	A species of parasitic nematode usually found in domestic pigs and a few other animals. Human infection can also occur, presumably as result of handling pig manure, and can lead to intestinal obstruction.	Ascaris suums,suum, Ascaris