On the first day of the development of acute coronary insufficiency there appears a spastic state of all the vascular system of the small intestine mesentery and a deceleration of the blood flow. On the third day after ligation of the coronary artery branch against the background of spasmed arterioles the alternation of sites of constricted and dilated capillaries, postcapillaries and venules was observed, i.e., there was a well pronounced spasticatonical state of the microcirculation bed vessels. On the fifth and seventh day the characteristic features were dilatation and decreased tonus of the venous part of the microcirculatory bed, redistribution of blood and more considerable disorders in microcirculation with aggregation and diapedesis of erythrocytes.