Biomaterial Database

Experimental evaluation of a new implant material in frontal sinus obliteration: a preliminary report. 1976

N L Schenck, and M J Tomlinson, and C D Ridgley

Frontal osteoplasty with exogenous material has been uniformly unsuccessful both experimentally and clinically. Our experiment was designed to test the long-term behavior of a new poly (tetrafluoroethylene)-carbon fiber implant material (Proplast) in a canine frontal sinus model. Varying conditions such as removal of the sinus mucoperiosteum, closure of the nasofrontal ducts, exposure of dura mater, and cerebrospinal fluid leaks were studied at intervals up to one year. Proplast was 100% successful in obliteration of the canine frontal sinus. The ultraporous nature allowed rapid vascularization, collagen ingrowth, and new bone formation, and led to stabilization rather than sequestration. Frontal obliteration with Proplast may be clinically superior to osteoplasty with any other presently available exogenous material or with osteoneogenesis alone, and may even obviate the few complications encountered with adipose implants. Only longer range experimental and clinical evaluation will provide the answer.

UI	MeSH Term	Description	Entries
D010027	Osteotomy	The surgical cutting of a bone. (Dorland, 28th ed)	Osteotomies
D011183	Postoperative Complications	Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D003238	Connective Tissue	Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.	Connective Tissues,Tissue, Connective,Tissues, Connective
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D004388	Dura Mater	The outermost of the three MENINGES, a fibrous membrane of connective tissue that covers the brain and the spinal cord.	Falx Cerebelli,Falx Cerebri,Pachymeninx,Tentorium Cerebelli
D005465	Fluorocarbon Polymers		Fluorinated Polymer,Fluorinated Polymers,Fluorocarbon Polymer,Fluorocarbon Resin,Fluorocarbon Resins,Fluoropolymers,Fluoropolymer,Polymer, Fluorinated,Polymer, Fluorocarbon,Polymers, Fluorinated,Polymers, Fluorocarbon,Resin, Fluorocarbon,Resins, Fluorocarbon
D005626	Frontal Sinus	One of the paired, but seldom symmetrical, air spaces located between the inner and outer compact layers of the FRONTAL BONE in the forehead.	Agger Nasi Cell,Frontal Recess,Frontal Sinus Ostium,Agger Nasi Cells,Cell, Agger Nasi,Frontal Recesses,Frontal Sinus Ostiums,Recess, Frontal,Sinus Ostium, Frontal,Sinus Ostiums, Frontal,Sinus, Frontal
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012852	Sinusitis	Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.	Sinus Infections,Infection, Sinus,Infections, Sinus,Sinus Infection,Sinusitides
D014945	Wound Healing	Restoration of integrity to traumatized tissue.	Healing, Wound,Healings, Wound,Wound Healings